1,4-Bis(2-chloroethoxy)benzene

Base Information

• Chemical Name: 1,4-Bis(2-chloroethoxy)benzene
• CAS No.: 37142-37-3
• Molecular Formula: C10H12Cl2O2
• Molecular Weight: 235.11
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID00401578
• Wikidata: Q82204756
• Mol file: 37142-37-3.mol

Synonyms:1,4-bis(2-chloroethoxy)benzene;37142-37-3;SCHEMBL5636691;DTXSID00401578;MFCD00222550;AKOS005070642;CS-0332543;FT-0663243;4Y-0018;A874175;J-503967

Chemical Property of 1,4-Bis(2-chloroethoxy)benzene

Chemical Property:

• Melting Point: 92-93°
• PSA: 18.46000
• LogP: 2.92180
• Solubility.: Acetone, Chloroform, Dichloromethane, Ethyl Acetate, Tetrahydrofuran
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 234.0214350
• Heavy Atom Count: 14
• Complexity: 120

Purity/Quality:

97% ^*data from raw suppliers

1,4-Bis(2-chloroethoxy)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1OCCCl)OCCCl

Technology Process of 1,4-Bis(2-chloroethoxy)benzene

There total 6 articles about 1,4-Bis(2-chloroethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,4-bis(2-hydroxyethoxy)benzene (104-38-1) → 1,4-Bis(2-chloroethoxy)benzene (37142-37-3)

Guidance literature:

With pyridine; thionyl chloride; at 20 ℃;

DOI:10.1021/jm000491y

Reference yield: 44.0%

1,2-dichloro-ethane (107-06-2,52399-93-6) + hydroquinone (123-31-9,8027-02-9) → 1,4-Bis(2-chloroethoxy)benzene (37142-37-3)

Guidance literature:

With potassium hydroxide; Aliquat; for 16h;

DOI:10.1002/recl.19931121207

Reference yield: 32.0%

1-Bromo-2-chloroethane (107-04-0) + hydroquinone (123-31-9,8027-02-9) → 1,4-Bis(2-chloroethoxy)benzene (37142-37-3)

Guidance literature:

With potassium carbonate; In acetone; for 24h; Heating;

DOI:10.1021/jm960199j

upstream raw materials:

1,2-dichloro-ethane

hydroquinone

1-Bromo-2-chloroethane

1,4-bis(2-hydroxyethoxy)benzene

Downstream raw materials:

5,7,12,13b,13c,14-Hexahydro-1,4,8,11-tetrakis(2-chlorethoxy)-13b,13c-diphenyl-6H,13H-5a,6a,12a,13a-tetraazabenz<5,6>azuleno<2,1,8-ija>benzazulene-6,13-dione

4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene

(S)-(+)-1-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane

(R)-(-)-1-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b;4,5-b']difuran-4-yl)-2-aminopropane