Z-L-Phenylalanine N-carboxyanhydride

Base Information

Chemical Name:Z-L-Phenylalanine N-carboxyanhydride
CAS No.:25613-60-9
Molecular Formula:C18H15 N O5
Molecular Weight:325.319
Hs Code.:2934999090
Mol file:25613-60-9.mol

Synonyms:3-Oxazolidinecarboxylicacid, 2,5-dioxo-4-(phenylmethyl)-, phenylmethyl ester, (S)-;3-Oxazolidinecarboxylic acid, 4-benzyl-2,5-dioxo-, benzyl ester, L- (8CI);(S)-4-Benzyl-3-benzyloxycarbonyl-2,5-oxazolidinedione

Suppliers and Price of Z-L-Phenylalanine N-carboxyanhydride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyl4-benzyl-2,5-dioxooxazolidine-3-carboxylate 97%
1g
$ 465.00

Total 13 raw suppliers

Chemical Property of Z-L-Phenylalanine N-carboxyanhydride

Chemical Property:

Melting Point:108-109 °C
Boiling Point:451.3±38.0 °C(Predicted)
PKA:-3.09±0.40(Predicted)
PSA：72.91000
Density:1.353±0.06 g/cm3(Predicted)
LogP:2.85120

Purity/Quality:

98% ^*data from raw suppliers

(S)-Benzyl4-benzyl-2,5-dioxooxazolidine-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Z-L-Phenylalanine N-carboxyanhydride

There total 3 articles about Z-L-Phenylalanine N-carboxyanhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 64-17-5
ethanol

: 25613-61-0
4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester

: 25613-60-9
Nα-carbobenzyloxy-L-phenylalanine N-carboxanhydride

: 95832-31-8
Z-D-phenylalanine ethyl ester

Guidance literature:: 4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester; With ethanol; O-propargylquinidine; In diethyl ether; at 20 ℃; for 0.25h; Molecular sieve;

ethanol; In diethyl ether; at -60 ℃; for 20h; Reagent/catalyst; enantioselective reaction;
DOI:10.1021/op700023h

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 14825-82-2
L-phenylalanine-N-carboxyanhydride

: 25613-60-9
Nα-carbobenzyloxy-L-phenylalanine N-carboxanhydride

Guidance literature:: With 4-methyl-morpholine; In tetrahydrofuran; at 2 - 5 ℃; for 2h; Yield given;
DOI:10.1021/ja00176a063

Reference yield:

: 64-17-5
ethanol

: 25613-61-0
4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester

: 28709-70-8
N-benzyloxycarbonyl-L-phenylalanine ethyl ester

: 25613-60-9
Nα-carbobenzyloxy-L-phenylalanine N-carboxanhydride

: 95832-31-8
Z-D-phenylalanine ethyl ester

Guidance literature:: 4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester; With ethanol; 9-O-propargylquinine; In diethyl ether; at 20 ℃; for 0.25h; Molecular sieve;

ethanol; In diethyl ether; at -60 ℃; for 20h; Reagent/catalyst; enantioselective reaction;
DOI:10.1021/op700023h