95832-31-8

Basic information

• Product Name: D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethyl ester
• CAS NO: 95832-31-8
• Molecular Formula: C19H21NO4
• Molecular Weight: 327.38
• Mol File: 95832-31-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethyl ester(95832-31-8)
• EPA Substance Registry System: D-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethyl ester(95832-31-8)

Safety Data

• Hazardous Substances Data: 95832-31-8(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 25613-61-0 4-Benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid benzyl ester 
• 212776-37-9 2-(N-(benzyloxycarbonyl)amino)-2-benzylpropanedioic diethyl ester 
• 3005-66-1 diethyl 2-benzyloxycarbonylaminomalonate 
• 100-39-0 benzyl bromide 

Downstream Products

• 95832-30-7 N-<(benzyloxy)carbonyl>-(2R)-amino-1-phenylbut-3-ene 
• 59969-65-2 (2S,3R)-3-benzyloxycarbonylamino-2-hydroxy-4-phenyl-butanoic acid 
• 59554-14-2 (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid 
• 95832-37-4 (4R,5S)-5-benzyl-4-(hydroxymethyl)-1,3-oxazolidin-2-one 
• 95832-38-5 methyl (4R,5S)-2-oxo-4-phenylmethyl-1,3-oxazolidine-5-carboxylate 
• 95891-28-4 (4R,5S)-3,4-Dibenzyl-5-hydroxymethyl-oxazolidin-2-one 
• 95832-34-1 Benzyl-((R)-1-benzyl-allyl)-carbamic acid benzyl ester 
• 60016-66-2 benzyl N-[(2S,3R)-3-(N-benzyloxycarbonyl)amino-2-hydroxy-4-phenylbutanoyl]-L-leucinate 
• 95832-36-3 (4R,5R)-3,4-Dibenzyl-5-iodomethyl-oxazolidin-2-one 
• 95832-35-2 (4R,5S)-3,4-Dibenzyl-5-iodomethyl-oxazolidin-2-one 
• 58970-76-6 bestatin 

Relevant articles and documents

Towards a universal organocatalyst for the synthesis of enantioenriched phenylalanine derivatives by enantioselective decarboxylative protonation

Access to enantioenriched non-proteogenic phenylalanine derivatives is described using the enantioselective decarboxylative protonation reaction of amidohemimalonate esters catalysed by various cinchona-based compounds. This study compares the catalytic efficiency as well as the enantioselectivity induced by three types of common organocatalysts, namely thioureas, squaramides and bis-cinchona squaramides. One of the main outcome of this work is the observation of a significant influence of the N-protecting group of the hemimalonate on its interaction with the catalyst. This methodology carried out under mild conditions exhibits good substrate scope and functional group tolerance. A substoichiometric amount of catalyst can also be used in certain cases while affording good yields and selectivities.