(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Base Information

Chemical Name:(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate
CAS No.:1313587-27-7
Molecular Formula:C₂₈H₄₄O₅
Molecular Weight:460.654
Hs Code.:

Synonyms:(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Suppliers and Price of (1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

There total 2 articles about (1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1313587-26-6
(1Z,2S,3S,4R,5R,6R,7R)-1-ethylidene-5,7-dihydroxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

: 77-76-9
2,2-dimethoxy-propane

: 1313587-27-7
(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Guidance literature:: With toluene-4-sulfonic acid; at 5 - 20 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201100196

Reference yield:

: C₃₇H₅₉BO₅

: 1313587-27-7
(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / methanol; diethyl ether; hexane / 5 h / -78 °C / Inert atmosphere

1.2: 14 h / -5 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / 5 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; toluene-4-sulfonic acid; In methanol; diethyl ether; hexane;
DOI:10.1002/ejoc.201100196

Reference yield: 74.0%

: 1313587-27-7
(1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate

: 15186-48-8
2,3-isopropylidene-glyceraldehyde

: 1313587-42-6
(+)-(2R,3S,4S,6S,7S,8S,9R,10R,11R)-3-hydroxy-1,1:9,11-bis(isopropylidenedioxy)-4,6,8,10-tetramethyl-7-[(1S)-1-phenylethoxy]dodecan-5-one

Guidance literature:: (1Z,2S,3S,4S,5R,6R,7R)-1-ethylidene-5,7-isopropylidenedioxy-2,4,6-trimethyl-3-[(1S)-1-phenylethoxy]octyl isobutyrate; With methyllithium lithium bromide; In diethyl ether; at -78 ℃; for 2h;

2,3-isopropylidene-glyceraldehyde; In diethyl ether; at -78 ℃; for 16h; diastereoselective reaction;
DOI:10.1002/ejoc.201100196