S-2-Aminoctanoic acid

Base Information

• Chemical Name: S-2-Aminoctanoic acid
• CAS No.: 116783-26-7
• Molecular Formula: C8H17 N O2
• Molecular Weight: 159.228
• Mol file: 116783-26-7.mol

Synonyms:Octanoicacid, 2-amino-, (S)-; (S)-2-Aminocaprylic acid; (S)-2-Aminooctanoic acid;L-2-Aminocaprylic acid; L-2-Aminooctanoic acid; L-a-Aminooctanoic acid

Chemical Property of S-2-Aminoctanoic acid

Chemical Property:

• Melting Point: 254-256 °C
• Boiling Point: 267.8±23.0 °C(Predicted)
• PKA: 2.55±0.24(Predicted)
• PSA: 63.32000
• Density: 0.999±0.06 g/cm3(Predicted)
• LogP: 2.06900
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-AminooctanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-2-Aminoctanoic acid

There total 19 articles about S-2-Aminoctanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

Octanoic acid (124-07-2) → (S)-α-aminooctanoic acid (116783-26-7,2187-07-7)

Guidance literature:

Octanoic acid; With P_450CLA; dihydrogen peroxide; In aq. phosphate buffer; ethanol; at 20 ℃; for 20h; pH=7; Enzymatic reaction;

With D-HIC-DH; L-HIC-DH; L-Phe-DH; NAD; ammonium carbonate; ammonium chloride; In aq. phosphate buffer; ethanol; at 20 ℃; for 24h; pH=8; enantioselective reaction; Enzymatic reaction;

DOI:10.1002/adsc.201801377

Reference yield:

2-oxooctanoic acid (328-51-8) + (S)-1-phenyl-ethylamine (2627-86-3) → (S)-α-aminooctanoic acid (116783-26-7,2187-07-7) + acetophenone (98-86-2)

Guidance literature:

With L57A/W58A/V154A triple mutant ω-transaminase from Ochrobactrum anthropi; In aq. phosphate buffer; at 37 ℃; pH=7; Reagent/catalyst; Kinetics; Enzymatic reaction;

DOI:10.1002/adsc.201900184

Reference yield:

1-Iodohexane (638-45-9) + glycine (56-40-6,18875-39-3,25718-94-9) → (R)-α-aminooctanoic acid (106819-03-8,2187-07-7) + (S)-α-aminooctanoic acid (116783-26-7,2187-07-7)

Guidance literature:

glycine; With pyridine-2-carboxylic acid(2-benzoyl-phenyl)-amide; sodium methylate; nickel(II) nitrate; In methanol; for 0.333333h; Heating;

1-Iodohexane; With sodium hydroxide; (R)-2-amino-2'-hydroxy-1,1'-binaphthyl; In dichloromethane; at 20 ℃; for 1h;

With hydrogenchloride; In methanol; water; Heating;

DOI:10.1002/1521-3773(20010518)40:10<1948::AID-ANIE1948>3.0.CO;2-O

upstream raw materials:

2-benzoylamino-octanoic acid

N-Dichloracetyl-DL-2-amino-octansaeure

2-aminooctanoic acid

1-Iodohexane

Downstream raw materials:

(S)-2-(3-((S)-1-carboxyheptyl)ureido)-6-(4-iodobenzamido)hexanoic acid