2-amino-3-(4-cyanophenyl)propanoic Acid

Base Information

Chemical Name:2-amino-3-(4-cyanophenyl)propanoic Acid
CAS No.:22888-47-7
Molecular Formula:C₁₀H₁₀N₂O₂
Molecular Weight:190.202
Hs Code.:2926909090
DSSTox Substance ID:DTXSID70394468
Mol file:22888-47-7.mol

Synonyms:2-amino-3-(4-cyanophenyl)propanoic Acid;22888-47-7;4-Cyano-DL-Phenylalanine;D-4-Cyanophenylalanine;L-(S)-4-Cyanophenylalanine;h-4-cyano-phe-oh;ammoniumbenzoate;l-4-cyanophe;2-Amino-3-(4-cyanophenyl)propanoicacid;4-cyano-L-Phenylaminine;H-DL-Phe(4-CN)-OH;SCHEMBL43593;DTXSID70394468;BCP11023;MFCD01862353;AKOS006278500;AM82775;PB48202;BS-49417;CS-0433721;DL-2-Amino-3-(4-cyanophenyl)propanoic acid;FT-0654229;FT-0658848;FT-0746844;A50211;EN300-1718844;4-Cyano-dl-phenylalanine (H-DL-Phe(4-CN)-OH)

Suppliers and Price of 2-amino-3-(4-cyanophenyl)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Cyano-DL-phenylalanine
500mg
$ 200.00

Crysdot
2-Amino-3-(4-cyanophenyl)propanoicacid 95+%
10g
$ 392.00

Chem-Impex
4-Cyano-DL-phenylalanine ≥ 99% (HPLC)
5G
$ 360.00

Chem-Impex
4-Cyano-DL-phenylalanine ≥ 99% (HPLC)
1G
$ 80.00

Chem-Impex
4-Cyano-DL-phenylalanine ≥ 99% (HPLC)
250MG
$ 30.00

Chemenu
2-Amino-3-(4-cyanophenyl)propanoicacid 95%
10g
$ 370.00

Biosynth Carbosynth
4-Cyanophenylalanine
500 mg
$ 80.00

Biosynth Carbosynth
4-Cyanophenylalanine
1 g
$ 193.20

Biosynth Carbosynth
4-Cyanophenylalanine
2 g
$ 353.50

Biosynth Carbosynth
4-Cyanophenylalanine
10 g
$ 905.00

Total 30 raw suppliers

Chemical Property of 2-amino-3-(4-cyanophenyl)propanoic Acid

Chemical Property:

Melting Point:221 - 223 °C (methanol)
Boiling Point:394.1±37.0 °C(Predicted)
PKA:2.13±0.10(Predicted)
PSA：87.11000
Density:1.28
LogP:1.21298
Storage Temp.:2-8°C
XLogP3:-1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:190.074227566
Heavy Atom Count:14
Complexity:248

Purity/Quality:

97% ^*data from raw suppliers

4-Cyano-DL-phenylalanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)N)C#N

Technology Process of 2-amino-3-(4-cyanophenyl)propanoic Acid

There total 5 articles about 2-amino-3-(4-cyanophenyl)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 166167-94-8
2-Amino-3-(4-cyano-phenyl)-propionic acid ethyl ester

: 18910-26-4,22888-47-7
2-amino-3-(4-cyano-phenyl)-propionic acid

Guidance literature:: With hydrogenchloride; water; In tetrahydrofuran; for 12h;

Reference yield:

: 773837-37-9
sodium cyanide

: 1991-81-7,14173-41-2,24250-85-9,62561-75-5
p-iodophenylalanine

: 18910-26-4,22888-47-7
2-amino-3-(4-cyano-phenyl)-propionic acid

Guidance literature:: With C₁₈H₁₄CuIN₄; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 24h; Inert atmosphere; Sealed tube; UV-irradiation;
DOI:10.1002/adsc.201700213

Reference yield:

: 17201-43-3
4-cyanobenzyl bromide

: 18910-26-4,22888-47-7
2-amino-3-(4-cyano-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 24 h / 25 °C

2: hydrogenchloride; water / tetrahydrofuran / 12 h

With hydrogenchloride; tetrabutylammomium bromide; water; potassium carbonate; In tetrahydrofuran; acetonitrile;