(2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate

Base Information

• Chemical Name: (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate
• CAS No.: 702711-17-9
• Molecular Formula: C₂₁H₂₃NO₅Se
• Molecular Weight: 448.377
• Mol file: 702711-17-9.mol

Synonyms:(2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate

Chemical Property of (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate

There total 2 articles about (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

benzoyl isocyanate (4461-33-0) + (2R)-2-hydroxy-3-(phenylseleno)propylbutyrate (702711-08-8) → (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate (702711-17-9)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1002/chem.200305497

Reference yield:

diphenyl diselenide (1666-13-3) → (2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate (702711-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 2 h / Heating

1.2: 25 percent / tetrahydrofuran; hexamethylphosphoric acid triamide / 1 h / 20 °C

2.1: 67 percent / CH₂Cl₂ / 20 °C

With sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200305497

Reference yield:

(2R)-2-{[(benzoylamino)carbonyl]oxy}-3-(phenylseleno)propyl butyrate (702711-17-9) → C21H23NO6Se

Guidance literature:

With dipotassium hydrogenphosphate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; for 2h;

DOI:10.1002/chem.200305497

upstream raw materials:

benzoyl isocyanate

(2R)-2-hydroxy-3-(phenylseleno)propylbutyrate

diphenyl diselenide