H-NVA-OME HCL

Base Information

• Chemical Name: H-NVA-OME HCL
• CAS No.: 56558-30-6
• Molecular Formula: C6H14ClNO2
• Molecular Weight: 167.636
• Hs Code.: 2922499990
• Mol file: 56558-30-6.mol

Synonyms:L-Norvaline,methyl ester, hydrochloride (9CI);Methyl L-norvalinate hydrochloride;

Chemical Property of H-NVA-OME HCL

Chemical Property:

• Vapor Pressure: 0.319mmHg at 25°C
• Boiling Point: 197.5 °C at 760 mmHg
• Flash Point: 73.2 °C
• PSA: 52.32000
• LogP: 1.78910
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

(S)-Methyl2-AminopentanoateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-Methyl 2-Aminopentanoate Hydrochloride can be prepared to use as a pesticides.

Technology Process of H-NVA-OME HCL

There total 7 articles about H-NVA-OME HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 2-aminopentanoic acid (hydrochloride) (848613-42-3) → norvaline methyl ester hydrochloride (10047-10-6,56558-30-6,619330-91-5)

Guidance literature:

With oxalyl dichloride; at 0 - 60 ℃; for 0.5h;

Reference yield: 98.0%

methanol (67-56-1) + L-Norvaline (6600-40-4,498-18-0) → methyl L-norvalinate hydrochloride (56558-30-6,619330-91-5)

Guidance literature:

With hydrogenchloride; Ambient temperature;

Reference yield:

L-Norvaline (6600-40-4,498-18-0) → methyl L-norvalinate hydrochloride (56558-30-6,619330-91-5)

Guidance literature:

In methanol;

upstream raw materials:

methanol

L-Norvaline

tert-butyl-(2S,3S)-1,2-dihydroxyhexan-3-ylcarbamate

acetyl chloride

Downstream raw materials:

N- norvaline methyl ester

2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-pentanoic acid methyl ester

methyl N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-norvalinate

Refernces

• 1、 Zhang, Yong-Kang,Plattner, Jacob J.,Easom, Eric E.,Jacobs, Robert T.,Guo, Denghui,Freund, Yvonne R.,Berry, Pamela,Ciaravino, Vic,Erve, John C. L.,Rosenthal, Philip J.,Campo, Brice,Gamo, Francisco-Javier,Sanz, Laura M.,Cao, Jianxin. "Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate". . p. 5889 - 5908. Retrieved 2017/07/22.
• 2、 -. "SYNTHESIS OF AN INTERMEDIATE OF AN ANTIVIRAL COMPOUND". Page/Page column 21-22. . Retrieved 2013/09/26.