(1R,2S)-2-benzamidocyclohexanecarboxylate

Base Information

• Chemical Name: (1R,2S)-2-benzamidocyclohexanecarboxylate
• CAS No.: 1226708-31-1
• Molecular Formula: C₁₅H₁₉NO₃
• Molecular Weight: 261.321
• Mol file: 1226708-31-1.mol

Synonyms:(1R,2S)-2-benzamidocyclohexanecarboxylate

Chemical Property of (1R,2S)-2-benzamidocyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2S)-2-benzamidocyclohexanecarboxylate

There total 1 articles about (1R,2S)-2-benzamidocyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.1%

methanol (67-56-1) + cis-(1R,2S)-2-benzamidocyclohexanecarboxylic acid → (1R,2S)-2-benzamidocyclohexanecarboxylate (1226708-31-1)

Guidance literature:

With sulfuric acid; for 12h; Reflux;

DOI:10.1002/cjoc.201090036

Reference yield: 93.1%

(1R,2S)-2-benzamidocyclohexanecarboxylate (1226708-31-1) + phenylmagnesium bromide (1589-82-8) → (1R,2S)-2-benzylaminocyclohexyl(diphenyl)methanol (1220104-27-7)

Guidance literature:

(1R,2S)-2-benzamidocyclohexanecarboxylate; phenylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 12.8333h; Reflux;

With lithium aluminium tetrahydride; In tetrahydrofuran; Reflux;

DOI:10.1002/cjoc.201090036

upstream raw materials:

methanol

Downstream raw materials:

(1R,2S)-2-benzylaminocyclohexyl(diphenyl)methanol