4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane
• CAS No.: 916658-71-4
• Molecular Formula: C₁₅H₂₃BO₂
• Molecular Weight: 246.157
• Mol file: 916658-71-4.mol

Synonyms:4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane

There total 18 articles about 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-phenylpropene (637-50-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane (916658-71-4) + 4,4,5,5-tetramethyl-2-(1-phenylpropan-2-yl)-1,3,2-dioxaborolane (916658-74-7) + 4,4,5,5-tetramethyl-2-(3-phenylpropyl)-[1,3,2]dioxaborolane (329685-40-7)

Guidance literature:

[(η4-1,5-cyclooctadiene)Rh(κ2-P,N-3-P(i)Pr2-2-NMe2-indenide)]; In tetrahydrofuran-d8; THF-d8, room temp., 2 mol% of catalyst, 72 h; detected by NMR spectra;

DOI:10.1021/om060742m

Reference yield: 92.0%

1-propenylbenzene (873-66-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane (916658-71-4)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 25 ℃; for 0.0833333h; regioselective reaction; Catalytic behavior; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1021/acs.orglett.8b03431

Reference yield: 84.0%

1-phenylpropene (637-50-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(1-phenyl-propyl)-[1,3,2]dioxaborolane (916658-71-4)

Guidance literature:

With [1,4-bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; tris(pentafluorophenyl)borate; In 1,1-Dichloroethylene; at 70 ℃; for 9h;

DOI:10.1021/ja904142m

upstream raw materials:

1-phenylpropene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2,3-dimethyl-2,3-butane diol

allylbenzene

Downstream raw materials:

(R)-1-phenyl-1-propanol

(S)-1-phenyl-1-propanol