(R)-(+)-1,1,2-TRIPHENYL-1,2-ETHANEDIOL

Base Information

• Chemical Name: (R)-(+)-1,1,2-TRIPHENYL-1,2-ETHANEDIOL
• CAS No.: 95061-46-4
• Molecular Formula: C20H18O2
• Molecular Weight: 290.362
• Hs Code.: 29062990
• Mol file: 95061-46-4.mol

Synonyms:1,2-Ethanediol,1,1,2-triphenyl-, (R)-;(2R)-1,1,2-Triphenyl-1,2-ethanediol;(R)-1,1,2-Triphenyl-1,2-ethanediol;

Chemical Property of (R)-(+)-1,1,2-TRIPHENYL-1,2-ETHANEDIOL

Chemical Property:

• Vapor Pressure: 5.71E-09mmHg at 25°C
• Melting Point: 126 °C
• Refractive Index: 220 ° (C=1, EtOH)
• Boiling Point: 452.3 °C at 760 mmHg
• PKA: 12.87±0.29(Predicted)
• Flash Point: 210 °C
• PSA: 40.46000
• Density: 1.197 g/cm³
• LogP: 3.65610
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(R)-(+)-1,1,2-Triphenyl-1,2-ethanediol >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-(+)-1,1,2-TRIPHENYL-1,2-ETHANEDIOL

There total 31 articles about (R)-(+)-1,1,2-TRIPHENYL-1,2-ETHANEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(tert-butyldimethylsilanyloxy)-1,1,2-triphenylethanol → (R)-1,1,2-triphenylethane-1,2-diol (95061-46-4)

Guidance literature:

With phosphomolybdic acid hydrate; silica gel; In tetrahydrofuran; at 20 ℃; for 0.333333h;

DOI:10.1021/jo0502697

Reference yield: 95.0%

2R-2-[(2R,5R-2,5-dimethyl-1-phenyl-1-silacyclopentyl)oxy]-1,1,2-triphenylethanol → (R)-1,1,2-triphenylethane-1,2-diol (95061-46-4) + (2R,5R)-(-)-2,5-dimethyl-1-phenyl-1-silacyclopentane

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Ambient temperature;

DOI:10.1039/P19950000117

Reference yield: 89.4%

sodium methylate (124-41-4) + (R)-2-hydroxy-1,2,2-triphenylethyl (3S,5S,Z)-3-hydroxy-5-<(tetrahydro-2H-pyran-2-yl)oxy>-13-docosenoate (114375-72-3) → (R)-1,1,2-triphenylethane-1,2-diol (95061-46-4) + methyl (3S,5S,Z)-3-hydroxy-5-<(tetrahydro-2H-pyran-2-yl)oxy>-13-docosenoate

Guidance literature:

In methanol; for 0.5h; Ambient temperature;

DOI:10.1002/hlca.19870700522

upstream raw materials:

(S)-Methyl mandelate

2-hydroxy-2-phenylacetophenone

bromobenzene

(R)-methyl mandelate

Downstream raw materials:

(R)-2-hydroxy-1,2,2-triphenylethyl propionate

(R)-2-acetoxy-1,1,2-triphenylethanol

benzophenone

1,2,2-triphenylethan-1-one