2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Base Information

Chemical Name:2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane
CAS No.:148436-62-8
Molecular Formula:C₄₃H₄₉N₅O₁₀S₄
Molecular Weight:924.154
Hs Code.:

Synonyms:2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Suppliers and Price of 2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

There total 4 articles about 2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 116052-92-7
Toluene-4-sulfonic acid 2-[{2-[{2-[[(S)-3-(4-nitro-phenyl)-2-(toluene-4-sulfonylamino)-propyl]-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl}-(toluene-4-sulfonyl)-amino]-ethyl ester

: 148436-62-8
2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 5h;
DOI:10.1021/ja00226a063

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 148436-62-8
2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / Et₃N / acetonitrile / 8 h / Ambient temperature

2: 79 percent / Cs₂CO₃ / dimethylformamide / 5 h / 60 °C

With caesium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja00226a063

Reference yield:

: 116052-91-6
2-(2-{2-[(S)-2-Amino-3-(4-nitro-phenyl)-propylamino]-ethylamino}-ethylamino)-ethanol

: 148436-62-8
2-(4-Nitro-benzyl)-1,4,7,10-tetrakis-(toluene-4-sulfonyl)-1,4,7,10-tetraaza-cyclododecane

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / Et₃N / acetonitrile / 8 h / Ambient temperature

2: 79 percent / Cs₂CO₃ / dimethylformamide / 5 h / 60 °C

With caesium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja00226a063