1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

Base Information

Chemical Name:1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile
CAS No.:436850-19-0
Molecular Formula:C₁₇H₁₂N₄S
Molecular Weight:304.375
Hs Code.:

Synonyms:1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

Chemical Property:

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Technology Process of 1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

There total 3 articles about 1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 107922-02-1
1-(3-methyl-6-phenylimidazo[2,1-b][1,3]thiazol-2-yl)ethanone

: 109-77-3
malononitrile

: 436850-19-0
1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

Guidance literature:: With ammonium acetate; acetic acid; In benzene; Heating;
DOI:10.1081/SCC-120002134

Reference yield:

: 30748-47-1
5-acetyl-4-methylthiazole-2-amine

: 436850-19-0
1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / butan-1-ol / Heating

2: 82 percent / ammonium acetate; AcOH / benzene / Heating

With ammonium acetate; acetic acid; In butan-1-ol; benzene;
DOI:10.1081/SCC-120002134

Reference yield:

: 70-11-1
α-bromoacetophenone

: 436850-19-0
1-(3-methyl-(4H)-5-phenylimidazo[2,1-b]thiazol-2-yl)ethylidenemalononitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / butan-1-ol / Heating

2: 82 percent / ammonium acetate; AcOH / benzene / Heating

With ammonium acetate; acetic acid; In butan-1-ol; benzene;
DOI:10.1081/SCC-120002134