o-azidophenyl isopropyl ketone

Base Information

• Chemical Name: o-azidophenyl isopropyl ketone
• CAS No.: 74333-54-3
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.217
• Mol file: 74333-54-3.mol

Synonyms:o-azidophenyl isopropyl ketone

Chemical Property of o-azidophenyl isopropyl ketone

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-azidophenyl isopropyl ketone

There total 2 articles about o-azidophenyl isopropyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(2-aminophenyl)-2-methyl-1-propanone (27309-55-3) → o-azidophenyl isopropyl ketone (74333-54-3)

Guidance literature:

1-(2-aminophenyl)-2-methyl-1-propanone; With acetic acid; sodium nitrite; In water; at 0 ℃; for 1h; Inert atmosphere;

With sodium azide; In water; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol101040p

Reference yield:

anthranilic acid nitrile (1885-29-6) → o-azidophenyl isopropyl ketone (74333-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 0 - 20 °C

2: sodium nitrite; sodium azide; acetic acid / water / 2 h / 0 - 20 °C

With sodium azide; acetic acid; sodium nitrite; In tetrahydrofuran; water;

DOI:10.1039/c9cc06652g

Reference yield: 94.5%

o-azidophenyl isopropyl ketone (74333-54-3) → 3-(1'-methylethyl)-2,1-benzisoxazole (106718-49-4)

Guidance literature:

at 350 ℃; for 3h; spray vacuum pyrolysis;

upstream raw materials:

1-(2-aminophenyl)-2-methyl-1-propanone

anthranilic acid nitrile

Downstream raw materials:

3-(1'-methylethyl)-2,1-benzisoxazole

C₁₁H₁₄N₄O

C₁₁H₁₄N₄O