27309-55-3

Basic information

• Product Name: 1-Propanone, 1-(2-aminophenyl)-2-methyl-
• Synonyms: 1-Propanone,1-(2-aminophenyl)-2-methyl;2-isopropylcarbonylaniline;1-(2-amino-phenyl)-2-methyl-propan-1-one;(2-aminophenyl)(isopropyl)methanone;1-(2-Aminophenyl)-2-methyl-1-propanone
• CAS NO: 27309-55-3
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Mol File: 27309-55-3.mol
• Article Data: 35

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-(2-aminophenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(2-aminophenyl)-2-methyl-(27309-55-3)
• EPA Substance Registry System: 1-Propanone, 1-(2-aminophenyl)-2-methyl-(27309-55-3)

Safety Data

• Hazardous Substances Data: 27309-55-3(Hazardous Substances Data)

Usage

Type of compound

Ketone, Methyl ketone

Usage

Building block in the synthesis of various pharmaceuticals and organic compounds, used in research and development for the creation of new drugs and materials

Potential applications

Medicine, chemistry, and materials science

Versatility

Versatile chemical structure and reactivity

Upstream product

• 1885-29-6 anthranilic acid nitrile 
• 75-26-3 isopropyl bromide 
• 67-56-1 methanol 
• 551-93-9 2-aminoacetophenone 
• 108665-93-6 3-isopropyl-1,3-dihydroindol-2-one 
• 507-19-7 t-butyl bromide 
• 1071084-07-5 1-(2-iodophenyl)-2-methylpropan-1-one 
• 209223-84-7 1-(2′-bromophenyl)-2-methylpropan-1-one 
• 5408-59-3 1-(2-chlorophenyl)-2-methyl-propan-1-one 
• 116707-09-6 1-(2-fluorophenyl)-2-methylpropan-1-one 
• 552-89-6 2-nitro-benzaldehyde 
• 529-23-7 o-aminobenzaldehyde 
• 574754-03-3 C₁₀H₁₅NO 
• 920-39-8 isopropylmagnesium bromide 

Downstream Products

• 129122-46-9 2-(4-fluorophenyl)-4-(1-methylethyl)-3-quinoline-carboxylic acid, ethyl ester 
• 93330-81-5 4-isopropyl-2-phenyl-quinazoline 
• 16886-00-3 3-isopropyl indole 
• 1198291-10-9 1-[2-(Dimethylamino)phenyl]-2-methyl-1-propanone 
• 85847-59-2 N-(2-Isobutyryl-phenyl)-formamide 

Relevant articles and documents

Ir(iii)-Catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling for the synthesis of N-H indoles

Herein, an iridium(iii)-catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling of unprotected 2-alkenyl anilines is described. The developed method allows the synthesis of a variety of 3-substituted N-H indole scaffolds under undivided electrolytic conditions. Mechanistic studies suggest that the reaction proceeds through the electro-oxidation induced reductive elimination pathway.

Nickel/Photo-Cocatalyzed Asymmetric Acyl-Carbamoylation of Alkenes

An unprecedented asymmetric acyl-carbamoylation of pendant alkenes tethered on aryl carbamic chlorides with both aliphatic and aromatic aldehydes has been developed via the cooperative catalysis of a chiral nickel-PHOX complex and tetrabutylammonium decatungstate. This reaction represents the first example of merging hydrogen-atom-transfer photochemistry and asymmetric transition metal catalysis in difunctionalization of alkenes. Using this protocol, a variety of oxindoles bearing a challenging quaternary stereogenic center are furnished under mild conditions in highly enantioselective manner.

The Reaction of o-Aminoacetophenone N-Tosylhydrazone and CO2 toward 1,4-Dihydro-2H-3,1-benzoxazin-2-ones

A transition-metal-free reaction of o-aminoacetophenone N-tosylhydrazone and CO2 has been developed, leading to a series of 1,4-dihydro-2H-3,1-benzoxazin-2-ones in moderate to good yields. This procedure proceeds with the sequential fixation of CO2 by amino leading to carbamic acid and the intra- molecular insertion of hydroxyl to carbene. (Figure presented.).