(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

Base Information

Chemical Name:(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane
CAS No.:145351-77-5
Molecular Formula:C₂₃H₃₂O₅SSi
Molecular Weight:448.656
Hs Code.:

Synonyms:(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

Suppliers and Price of (1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

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Chemical Property of (1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

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Technology Process of (1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

There total 1 articles about (1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145351-74-2
(1S,2R,3S)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(2,2-diphenyl-vinyl)-cyclobutanol

: 145351-77-5
(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N / CH₂Cl₂ / Ambient temperature

2: 1) O₃, 2) NaBH₄ / 1) CH₂Cl₂, MeOH, -78 deg C, 2 h, 2) -78 deg C, 30 min

With sodium tetrahydroborate; ozone; triethylamine; In dichloromethane;

Reference yield: 95.0%

: 69739-34-0
t-butyldimethylsiyl triflate

: 145351-77-5
(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

: 145351-78-6
Methanesulfonic acid (1S,2S,3S)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(tert-butyl-diphenyl-silanyloxymethyl)-cyclobutyl ester

Guidance literature:: With triethylamine; In dichloromethane; for 1h; Ambient temperature;

Reference yield:

: 145351-77-5
(1S,2S,3S)1-Methylsulfonyloxy-2-hydroxymethyl-3-tert-butyldiphenylsilyloxymethylcyclobutane

: 145351-79-7
9-[(1R,2R,3S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-(tert-butyl-diphenyl-silanyloxymethyl)-cyclobutyl]-9H-purin-6-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Et₃N / CH₂Cl₂ / 1 h / Ambient temperature

2: 41 percent / NaH, 18-crown-6 / dimethylformamide / 16 h / 140 °C

With 18-crown-6 ether; sodium hydride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;