Technology Process of 4-bromo-4'-diphenyl ether boronic ester
There total 5 articles about 4-bromo-4'-diphenyl ether boronic ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; toluene-4-sulfonic acid;
In
diethyl ether; hexane; benzene;
soln. of 4-bromo-4'-iododiphenyl esther in Et2O degassed; cooled to -78°C; TMEDA added, n-BuLi in n-hexane added; stirred for 3 h at -78°C; soln. of (MeO)3B in Et2O added; mixt. stirred overnight; warmed to room temp.; 4 M HCl added ...; solvent evapd.; elem. anal.;
DOI:10.1021/ja021370l
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 99 percent / ICl; AcOH / 2 h / Heating
2.1: n-BuLi; TMEDA / diethyl ether; hexane / 3 h / -78 °C
2.2: diethyl ether; hexane / -78 °C
3.1: aq. HCl / diethyl ether; hexane
4.1: 1.06 g / p-TsOH / benzene / 2 h / Heating
With
hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; Iodine monochloride; toluene-4-sulfonic acid; acetic acid;
In
diethyl ether; hexane; benzene;
DOI:10.1021/ja021370l
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-BuLi; TMEDA / diethyl ether; hexane / 3 h / -78 °C
1.2: diethyl ether; hexane / -78 °C
2.1: aq. HCl / diethyl ether; hexane
3.1: 1.06 g / p-TsOH / benzene / 2 h / Heating
With
hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; toluene-4-sulfonic acid;
In
diethyl ether; hexane; benzene;
DOI:10.1021/ja021370l
