Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile

Base Information

Chemical Name:Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile
CAS No.:33630-46-5
Molecular Formula:C₉H₉NO₃
Molecular Weight:179.175
Hs Code.:
European Community (EC) Number:619-705-5
DSSTox Substance ID:DTXSID801346029
Nikkaji Number:J47.607B

Synonyms:33630-46-5;hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile;2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile;SCHEMBL77463;VHGYYIXSLHYRBH-UHFFFAOYSA-N;DTXSID801346029;MFCD01897649;AKOS009096603;SB84577;LS-07454;3-METHOXY-4-HYDROXY MANDELONITRILE;CS-0332830;Hydroxy-(4-hydroxy-3-methoxy-phenyl)-acetonitrile

Suppliers and Price of Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:179.058243149
Heavy Atom Count:13
Complexity:210

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C(C#N)O)O

Technology Process of Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile

There total 5 articles about Hydroxy(4-hydroxy-3-methoxyphenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 143-33-9,25596-52-5
sodium cyanide

: 121-33-5,8014-42-4
vanillin

: 33630-46-5
2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethannitril

Guidance literature:: With sulfuric acid; In water; at 15 - 20 ℃; for 6 - 8h; pH=6.0 - 6.5; Product distribution / selectivity;

Reference yield: 96.0%

: 74-90-8
hydrogen cyanide

: 121-33-5,8014-42-4
vanillin

: 33630-46-5
2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethannitril

Guidance literature:: With sodium hydroxide; sulfuric acid; In tert-butyl methyl ether; water; at 15 - 20 ℃; for 3.5 - 4h; pH=6.0 - 7.5; Product distribution / selectivity;

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 33630-46-5
2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)ethannitril

Guidance literature:: With aqueous sodium disulfite solution; anschliessendes Behandeln mit wss. Kaliumcyanid-Loesung;
DOI:10.1021/ja01335a058