Technology Process of (3R,4S)-4-methyl-1-phenylhex-5-en-3-yl acetate
There total 1 articles about (3R,4S)-4-methyl-1-phenylhex-5-en-3-yl acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1021/ja504228p
- Guidance literature:
-
With
caesium carbonate;
In
tetrahydrofuran; methanol;
at 70 ℃;
for 6h;
Inert atmosphere;
DOI:10.1021/ja504228p
- Guidance literature:
-
Multi-step reaction with 5 steps
1: caesium carbonate / tetrahydrofuran; methanol / 6 h / 70 °C / Inert atmosphere
2: dmap / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
3: sodium perborate monohydrate; water / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
4: 1H-imidazole / dichloromethane / 2 h / 20 °C / Inert atmosphere
5: potassium carbonate; methanol / 2.5 h / 20 °C / Inert atmosphere
With
1H-imidazole; methanol; dmap; sodium perborate monohydrate; water; potassium carbonate; caesium carbonate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja504228p
