Technology Process of C39H39NO2
There total 25 articles about C39H39NO2 which
guide to synthetic route it.
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synthetic route:
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151726-44-2
(1R,8aR)-1-(3-Benzyloxy-2-iodo-4-methoxy-benzyl)-2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-1,2,3,4,6,7,8,8a-octahydro-isoquinoline
- Guidance literature:
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With
1,2,2,6,6-pentamethylpiperidine; palladium (II) bis(triphenylphosphine) bis(trifluoroacetate);
In
toluene;
at 120 ℃;
- Guidance literature:
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Multi-step reaction with 10 steps
1: catechol borane, (S)-oxazaborolidine catalyst
3: OsO4, R3NO
4: H+
5: 1.) n-BuLi, 2.) CuI(Ph3P)2
6: p-TsOH / methanol / Ambient temperature
7: NaIO4
8: NaCNBH3
9: 5percent ZnI2 / ethanol / 60 °C
10: 60 percent / 10percent Pd(OCOCF3)2(PPh3)2, 1,2,2,6,6-pentamethylpiperidine / toluene / 120 °C
With
1,2,2,6,6-pentamethylpiperidine; sodium periodate; osmium(VIII) oxide; n-butyllithium; palladium (II) bis(triphenylphosphine) bis(trifluoroacetate); (triphenylphosphine)2CuI; (S)-oxazaborolidine catalyst; hydrogen cation; sodium cyanoborohydride; toluene-4-sulfonic acid; zinc(II) iodide; benzo[1,3,2]dioxaborole;
In
methanol; ethanol; toluene;
- Guidance literature:
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Multi-step reaction with 5 steps
1: 97 percent / K2CO3
2: 91 percent
3: 92 percent / BF3*OEt2 / tetrahydrofuran / Ambient temperature
4: 82 percent / 5percent ZnI2 / ethanol / 60 °C
5: 60 percent / 10percent Pd(OCOCF3)2(PPh3)2, 1,2,2,6,6-pentamethylpiperidine / toluene / 120 °C
With
1,2,2,6,6-pentamethylpiperidine; palladium (II) bis(triphenylphosphine) bis(trifluoroacetate); boron trifluoride diethyl etherate; potassium carbonate; zinc(II) iodide;
In
tetrahydrofuran; ethanol; toluene;