(4-Aminopyridin-3-yl)methanol

Base Information

Chemical Name:(4-Aminopyridin-3-yl)methanol
CAS No.:138116-34-4
Molecular Formula:C6H8N2O
Molecular Weight:124.142
Hs Code.:29333990
European Community (EC) Number:681-133-7
DSSTox Substance ID:DTXSID10444916
Wikidata:Q72441670
Mol file:138116-34-4.mol

Synonyms:4-aminopyridine-3-methanol;4-AP-3-Me0H

Suppliers and Price of (4-Aminopyridin-3-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Amino-pyridin-3-yl)-methanol
500mg
$ 110.00

TRC
(4-Amino-pyridin-3-yl)-methanol
100mg
$ 45.00

Sigma-Aldrich
(4-Amino-pyridin-3-yl)-methanol Aldrich
1g
$ 168.00

Matrix Scientific
(4-Amino-pyridin-3-yl)-methanol
5g
$ 445.00

Matrix Scientific
(4-Amino-pyridin-3-yl)-methanol
1g
$ 117.00

Frontier Specialty Chemicals
4-Aminopyridine-3-methanol 97%
1g
$ 234.00

Crysdot
(4-Aminopyridin-3-yl)methanol 97%
1g
$ 109.00

ChemScene
(4-Aminopyridin-3-yl)methanol 98.05%
1g
$ 108.00

Atlantic Research Chemicals
(4-Aminopyridin-3-yl)methanol 95%
1gm:
$ 166.12

American Custom Chemicals Corporation
(4-AMINO-PYRIDIN-3-YL)-METHANOL 95.00%
1G
$ 795.80

Total 53 raw suppliers

Chemical Property of (4-Aminopyridin-3-yl)methanol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:167-169℃
Refractive Index:1.628
Boiling Point:367.19 °C at 760 mmHg
PKA:13.54±0.10(Predicted)
Flash Point:175.871 °C
PSA：59.14000
Density:1.257 g/cm³
LogP:0.73730
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Air Sensitive
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:Slightly soluble in water.
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:124.063662883
Heavy Atom Count:9
Complexity:87.1

Purity/Quality:

97% ^*data from raw suppliers

(4-Amino-pyridin-3-yl)-methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,T+
Statements: 28-36/37/38
Safety Statements: 26-36/37/39-45-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC(=C1N)CO
Uses 4-Amino-3-pyridinemethanol is used as an organic chemical synthesis intermediate.

Technology Process of (4-Aminopyridin-3-yl)methanol

There total 9 articles about (4-Aminopyridin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 16135-36-7
methyl 4-aminonicotinate

: 138116-34-4
4-amino-3-hydroxymethylpyridine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; 1) 35 deg C, 3 h, 2) reflux, 1 h;
DOI:10.1080/00397919608004536

Reference yield: 80.0%

: 42373-30-8
4-aminonicotinaldehyde

: 138116-34-4
4-amino-3-hydroxymethylpyridine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmcl.2007.11.101

Reference yield:

: 1003-73-2
3-picoline-N-oxide

: 138116-34-4
4-amino-3-hydroxymethylpyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 51 percent / HNO₃, H₂SO₄ / 2 h

2: 68 percent / H₂SO₃, sodium dichromate / 3 h / 55 °C

3: 88 percent / H₂ / Pd/C / acetic acid / 2280 Torr / 1) 30 deg C, 2 h, 2) 60 deg C, 2 h

4: 49 percent / H₂SO₄ / 4 h / Heating

5: 90 percent / LiAlH₄ / tetrahydrofuran / 1) 35 deg C, 3 h, 2) reflux, 1 h

With lithium aluminium tetrahydride; sodium dichromate; sulfuric acid; hydrogen; nitric acid; sulphurous acid; palladium on activated charcoal; In tetrahydrofuran; acetic acid;
DOI:10.1080/00397919608004536