Technology Process of C18H19NO6
There total 3 articles about C18H19NO6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C16H17NO5; ethyl bromoacetate;
With
chloro-trimethyl-silane; zinc;
In
tetrahydrofuran;
for 3.16667h;
Inert atmosphere;
Reflux;
With
ammonium chloride;
In
tetrahydrofuran; water;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol202499g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1,4-diaza-bicyclo[2.2.2]octane; di-tert-butyl dicarbonate / toluene / 12 h / 30 °C / Inert atmosphere
2.1: chloro-trimethyl-silane; zinc / tetrahydrofuran / 3.17 h / Inert atmosphere; Reflux
2.2: 0 - 20 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; chloro-trimethyl-silane; di-tert-butyl dicarbonate; zinc;
In
tetrahydrofuran; toluene;
DOI:10.1021/ol202499g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1,4-diaza-bicyclo[2.2.2]octane; di-tert-butyl dicarbonate / toluene / 12 h / 30 °C / Inert atmosphere
2.1: chloro-trimethyl-silane; zinc / tetrahydrofuran / 3.17 h / Inert atmosphere; Reflux
2.2: 0 - 20 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; chloro-trimethyl-silane; di-tert-butyl dicarbonate; zinc;
In
tetrahydrofuran; toluene;
DOI:10.1021/ol202499g