tert-Butyl (4-bromopyridin-2-yl)carbamate

Base Information

Chemical Name:tert-Butyl (4-bromopyridin-2-yl)carbamate
CAS No.:207799-10-8
Molecular Formula:C10H13BrN2O2
Molecular Weight:273.129
Hs Code.:2933399090
European Community (EC) Number:817-281-8
DSSTox Substance ID:DTXSID40470526
Wikidata:Q72447878
Mol file:207799-10-8.mol

Synonyms:207799-10-8;tert-Butyl (4-bromopyridin-2-yl)carbamate;2-(Boc-amino)-4-bromopyridine;tert-butyl 4-bromopyridin-2-ylcarbamate;Tert-butyl N-(4-bromopyridin-2-yl)carbamate;MFCD09037866;tert-butyl(4-bromopyridin-2-yl)carbamate;tert-butyl N-(4-bromo-2-pyridyl)carbamate;Carbamic acid, N-(4-bromo-2-pyridinyl)-, 1,1-dimethylethyl ester;tert-butyl (4-bromopyrid-2-yl)carbamate;SCHEMBL1133582;AMY1776;DTXSID40470526;IRRRVCLDPODLJG-UHFFFAOYSA-N;BCP16880;AB2730;AKOS015892103;PB34352;AC-24540;SY029102;TS-03530;A4519;CS-0030415;FT-0648477;tert-Butyl(4-bromo-pyridin-2-yl)-carbamate;tert-Butyl (4-bromo-pyridin-2-yl)-carbamate;EN300-316719;2-Methyl-2-propanyl (4-bromo-2-pyridinyl)carbamate;J-013618;J-524363

Suppliers and Price of tert-Butyl (4-bromopyridin-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Boc-amino)-4-bromopyridine
250mg
$ 75.00

SynQuest Laboratories
2-(Boc-amino)-4-bromopyridine 95%
1 g
$ 104.00

SynChem
2-(BOC-AMINO)-4-BROMOPYRIDINE 95%
1 g
$ 132.00

Matrix Scientific
tert-Butyl (4-bromopyridin-2-yl)carbamate 95+%
1g
$ 310.00

Matrix Scientific
tert-Butyl (4-bromopyridin-2-yl)carbamate 95+%
5g
$ 993.00

Crysdot
tert-Butyl(4-bromopyridin-2-yl)carbamate 98%
25g
$ 545.00

Crysdot
tert-Butyl(4-bromopyridin-2-yl)carbamate 98%
10g
$ 253.00

Chemenu
tert-Butyl(4-bromopyridin-2-yl)carbamate 98%
10g
$ 239.00

Chemenu
tert-Butyl(4-bromopyridin-2-yl)carbamate 98%
5g
$ 143.00

Chemenu
tert-Butyl(4-bromopyridin-2-yl)carbamate 98%
25g
$ 514.00

Total 51 raw suppliers

Chemical Property of tert-Butyl (4-bromopyridin-2-yl)carbamate

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.573
Boiling Point:296.698 °C at 760 mmHg
PKA:11.89±0.70(Predicted)
Flash Point:133.239 °C
PSA：51.22000
Density:1.454 g/cm³
LogP:3.26410
Storage Temp.:Room temperature.
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:272.01604
Heavy Atom Count:15
Complexity:228

Purity/Quality:

99%, ^*data from raw suppliers

2-(Boc-amino)-4-bromopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC=CC(=C1)Br

Technology Process of tert-Butyl (4-bromopyridin-2-yl)carbamate

There total 1 articles about tert-Butyl (4-bromopyridin-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5470-66-6
2-methyl-4-nitropyridine N-oxide

: 207799-10-8
(4-bromopyridin-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: iron; acetic acid / 2 h / 20 - 100 °C

2: hydrogen bromide; sodium nitrite / water / 16.5 h / -10 - 20 °C

3: potassium permanganate / water / 6.5 h / 20 °C / Heating / reflux

With potassium permanganate; hydrogen bromide; iron; acetic acid; sodium nitrite; In water;

Reference yield: 100.0%

: 207799-10-8
(4-bromopyridin-2-yl)-carbamic acid tert-butyl ester

: 1001419-41-5
C₅H₅BrN₂*ClH

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 20h;

Reference yield: 84.0%

: 380430-56-8
(3-amino-5-(methoxycarbonyl)phenyl)boronic acid

: 207799-10-8
(4-bromopyridin-2-yl)-carbamic acid tert-butyl ester

: methyl 3-amino-5-{2-[(tert-butoxycarbonyl)amino]pyridin-4-yl}benzoate

Guidance literature:: With sodium carbonate; dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium dichloromethane; In diethylene glycol dimethyl ether; water; at 80 ℃; for 12h;