pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

Base Information

Chemical Name:pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester
CAS No.:1369590-59-9
Molecular Formula:C₁₈H₂₄N₂O₄
Molecular Weight:332.4
Hs Code.:

Synonyms:pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

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Chemical Property of pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

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Technology Process of pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

There total 2 articles about pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 29745-44-6
pyridine-2-carbonyl chloride

: 1369590-89-5
pyrrolidine-1-carboxylic acid 4-hydroxy-cyclohexylmethyl ester

: 1369590-59-9
pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 33893-85-5
4-(hydroxymethyl)cyclohexan-1-ol

: 1369590-59-9
pyridine-2-carboxylic acid 4-(pyrrolidine-1-carbonyloxymethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 2 h / 20 °C

1.2: 2 h / 60 °C

2.1: triethylamine / dichloromethane / 16 h / 20 °C

With triethylamine; In tetrahydrofuran; dichloromethane;