1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol

Base Information

• Chemical Name: 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol
• CAS No.: 1105675-58-8
• Molecular Formula: C₃₂H₄₁BrO₅
• Molecular Weight: 585.579

Synonyms:1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol

Chemical Property of 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol

There total 1 articles about 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1 ,6-dibromohexane (629-03-8) + 2-[(4,4’-dimethoxytrityl)oxymethyl]-2-methylpropane-1,3-diol (327029-56-1) → 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol (1105675-58-8)

Guidance literature:

With sodium hydride; sodium iodide; In tetrahydrofuran; mineral oil; at 0 - 20 ℃;

DOI:10.1021/jo802536q

Reference yield: 75.0%

1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol (1105675-58-8) + potassium thioacetate (10387-40-3) → 1-O-(4,4'-dimethoxytrityl)-2-(6-S-acetylthiohexyloxymethyl)-2-methylpropane-1,3-diol

Guidance literature:

With 18-crown-6 ether; In toluene; at 50 ℃; for 2h;

Reference yield: 73.0%

1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol (1105675-58-8) + N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) → 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-3-O-[(2-cyanoethyl)-N,N-diisopropyl-phosphoramidite]-1,3-propanediol (1105675-59-9)

Guidance literature:

With N,N-diisopropylamine tetrazolide; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1021/jo802536q

upstream raw materials:

1 ,6-dibromohexane

2-[(4,4’-dimethoxytrityl)oxymethyl]-2-methylpropane-1,3-diol

Downstream raw materials:

1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-3-O-[(2-cyanoethyl)-N,N-diisopropyl-phosphoramidite]-1,3-propanediol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1105675-58-8 1-O-(4,4'-dimethoxytrityl)-2-(6-bromohexyloxymethyl)-2-methyl-1,3-propanediol

Send

Send

Metric Ton KG G Pound L ML

Send

Send