6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Base Information

Chemical Name:6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol
CAS No.:1286189-15-8
Molecular Formula:C₁₇H₁₄Br₂O₂
Molecular Weight:410.105
Hs Code.:

Synonyms:6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Suppliers and Price of 6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Strem Chemicals
(R)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 95% (99% ee)
250mg
$ 218.00

Crysdot
(R)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol 97%
1g
$ 900.00

Crysdot
(R)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol 97%
100mg
$ 240.00

Total 2 raw suppliers

Chemical Property of 6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(R)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 95% (99% ee) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

There total 1 articles about 6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 223137-87-9,223259-62-9,223259-63-0
(R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

: 1286189-15-8,1621066-74-7,1807777-59-8
6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Guidance literature:: With N-Bromosuccinimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 6h; Inert atmosphere;
DOI:10.1021/ja200084a

Reference yield: 95.0%

: 1286189-15-8,1621066-74-7,1807777-59-8
6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

: 73852-19-4
3,5-bis-trifluromethylphenylboronic acid

: 1286189-16-9,1258327-01-3
C₃₃H₂₀F₁₂O₂

Guidance literature:: With palladium diacetate; potassium carbonate; catacxium A; In water; at 95 ℃; for 6h; Inert atmosphere;
DOI:10.1021/ja200084a

Reference yield: 51.0%

: 76-86-8
Triphenylsilyl chloride

: 1286189-15-8,1621066-74-7,1807777-59-8
(R)-6,6'-dibromo-1,1'-spirobiindane-7,7'-diol

: 1372719-97-5
(R)-6,6'-bis(triphenylsilyl)-1,1'-spirobiindane-7,7'-diol

Guidance literature:: Triphenylsilyl chloride; (R)-6,6'-dibromo-1,1'-spirobiindane-7,7'-diol; With 1H-imidazole; In N,N-dimethyl-formamide; at 120 ℃; for 16h;

With tert.-butyl lithium; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/ejoc.201101739