2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Base Information

Chemical Name:2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine
CAS No.:1542796-11-1
Molecular Formula:C₂₄H₂₆NO₃P
Molecular Weight:407.449
Hs Code.:

Synonyms:2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Suppliers and Price of 2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-((2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine 95%+
1g
$ 1472.00

Chemenu
2-((2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine 95%+
500mg
$ 736.00

Chemenu
2-((2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine 95%+
100mg
$ 184.00

Total 2 raw suppliers

Chemical Property of 2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Chemical Property:

Boiling Point:527.0±50.0 °C(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-((2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

There total 4 articles about 2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1542795-98-1
(2R,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2-(pyridin-2-yl)-2H-benzo[d][1,3]oxaphosphole-3-oxide

: 1542796-11-1
2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Guidance literature:: With titanium(IV) isopropylate; In tetrahydrofuran; at 65 ℃; for 14h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo4024864

Reference yield: 75.0%

: 1542796-11-1
2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Guidance literature:: With titanium(IV) isopropylate; In tetrahydrofuran; at 65 ℃; for 14h; Inert atmosphere; Schlenk technique;

Reference yield:

: 24244-60-8
2-(phenylsulfonyl)pyridine

: 1542796-11-1
2-((2R,3R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; ethylbenzene / 1 h / -78 - -70 °C / Inert atmosphere

1.2: 2 h / -78 - 20 °C

2.1: titanium(IV) isopropylate / tetrahydrofuran / 14 h / 65 °C / Inert atmosphere; Schlenk technique

With titanium(IV) isopropylate; lithium diisopropyl amide; In tetrahydrofuran; ethylbenzene;
DOI:10.1021/jo4024864