methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

Base Information

Chemical Name:methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate
CAS No.:1259320-66-5
Molecular Formula:C₁₈H₁₆F₆N₄O₃
Molecular Weight:450.34
Hs Code.:

Synonyms:methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

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Chemical Property of methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

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Technology Process of methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

There total 1 articles about methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 67-56-1
methanol

: 1259320-63-2
4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)butyric acid

: 1259320-66-5
methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

Guidance literature:: sulfuric acid; at 25 ℃; for 16h;

Reference yield:

: 1259320-66-5
methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate

: 1259320-64-3
2-(R)-4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)butyric acid

Guidance literature:: methyl 4-oxo-2-(2,4,5-trifluorobenzyl)-4-(3-trifluoromethyl-5,6-dihydro[1,2,4]triazolo[4,3-a]-7(8H)-pyrazinyl)-butyrate; With water; sodium hydroxide; In toluene; at 50 ℃; for 6h; pH=7 - 8.5; Aqueous phosphate buffer; Enzymatic reaction;

With hydrogenchloride; In water; pH=1;