Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester

Base Information

• Chemical Name: Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester
• CAS No.: 787548-29-2
• Molecular Formula: C8H13 N O2
• Molecular Weight: 155.197
• Mol file: 787548-29-2.mol

Synonyms:Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester

Chemical Property of Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester

Chemical Property:

• Vapor Pressure: 0.563mmHg at 25°C
• Boiling Point: 189.675oC at 760 mmHg
• Flash Point: 61.357oC
• PSA: 52.32000
• Density: 1.156g/cm3
• LogP: 1.15320
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-amino-2-vinylcyclopropanecarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester

There total 6 articles about Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(E)-1,4-dibromobutene (821-06-7) + ethyl N-benzylideneglycinate (40682-54-0) → (1R,2S)/(1S,2R) 1-amino-2-vinylcyclopropane carboxylic acid ethyl ester (787548-29-2,213316-32-6,259221-73-3)

Guidance literature:

(E)-1,4-dibromobutene; ethyl N-benzylideneglycinate; With ethanol; sodium; In toluene; at 0 ℃; for 2h;

With hydrogenchloride; In water; toluene; at 0 - 30 ℃; Solvent;

Reference yield:

C21H21NO2 (1023795-84-7) → (1R,2S)/(1S,2R) 1-amino-2-vinylcyclopropane carboxylic acid ethyl ester (787548-29-2,213316-32-6,259221-73-3)

Guidance literature:

With hydrogenchloride; In diethyl ether; water; at 20 ℃; for 3.5h;

Reference yield:

(E)-ethyl 1-(benzylideneamino)-2-vinylcyclopropanecarboxylate (1393095-18-5) → (1R,2S)/(1S,2R) 1-amino-2-vinylcyclopropane carboxylic acid ethyl ester (787548-29-2,213316-32-6,259221-73-3)

Guidance literature:

(E)-ethyl 1-(benzylideneamino)-2-vinylcyclopropanecarboxylate; With hydrogenchloride; water; In tert-butyl methyl ether; at 20 ℃; for 2h;

With sodium hydroxide; In tert-butyl methyl ether; water; pH=14;

upstream raw materials:

(E)-1,4-dibromobutene

[(benzylidene)amino]acetic acid ethyl ester

C₂₁H₂₁NO₂

(E)-ethyl 1-(benzylideneamino)-2-vinylcyclopropanecarboxylate

Downstream raw materials:

(1R,2S)-ethyl 1-amino-2-vinylcyclopropanecarboxylate hydrochloride

(1R)-1-[[[(1R,2R,4R)-2-[[[(1S)-1-[[[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-4-hydroxycyclopentyl]carbonyl]amino]-2-ethenyl-cyclopropanecarboxylic acid ethyl ester

(1RS,2SR)-ethyl 2-vinyl-1-(tert-butoxycarbonylamino)cyclopropanecarboxylate

(trans)-ethyl 1-amino-2-vinylcyclopropanecarboxylate hydrochloride