(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

Base Information

Chemical Name:(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate
CAS No.:1643319-34-9
Molecular Formula:C₂₁H₃₆O₅Si
Molecular Weight:396.599
Hs Code.:

Synonyms:(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

Suppliers and Price of (2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

There total 2 articles about (2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 67-56-1
methanol

: 1643319-33-8
(2S,3R,E)-2-((tert-butyl)dimethylsilyloxy)-6-oxohex-4-en-3-yl benzoate

: 1643319-34-9
(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

: 1643319-36-1
(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6-methoxyhexan-3-yl benzoate

: 1643319-37-2
C₁₄H₂₀O₄

: 1643319-38-3
C₁₅H₂₂O₅

Guidance literature:: With palladium 10% on activated carbon; hydrogen; at 20 ℃; for 12h; under 750.075 Torr;
DOI:10.3762/bjoc.10.102

Reference yield:

: 67-56-1
methanol

: 1643319-33-8
(2S,3R,E)-2-((tert-butyl)dimethylsilyloxy)-6-oxohex-4-en-3-yl benzoate

: 1643319-34-9
(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

: 1643319-35-0
(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6-oxohexan-3-yl benzoate

Guidance literature:: With 10% palladium hydroxide on charcoal; hydrogen; at 20 ℃; for 12h; under 750.075 Torr; Overall yield = 83 %; Overall yield = 226 mg;
DOI:10.3762/bjoc.10.102

Reference yield:

: 1643319-34-9
(2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate

: C₁₃H₁₈O₃

: (S)-1-((R)-5-hydroxytetrahydrofuran-2-yl)ethyl benzoate

: C₁₃H₁₆O₄

Guidance literature:: (2S,3R)-2-((tert-butyl)dimethylsilyloxy)-6,6-dimethoxyhexan-3-yl benzoate; With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 20 ℃; for 4h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 12h; Overall yield = 71 %; Overall yield = 112 mg; Inert atmosphere;
DOI:10.3762/bjoc.10.102