7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Base Information

Chemical Name:7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate
CAS No.:1372854-73-3
Molecular Formula:C₂₄H₃₄N₅O₁₇P₃
Molecular Weight:757.479
Hs Code.:

Synonyms:7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Suppliers and Price of 7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

There total 25 articles about 7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1372854-71-1
7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-7-deaza-2'-deoxyguanosine

: 1372854-73-3
7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; trichlorophosphate / 6.5 h / 0 °C / Inert atmosphere

2.1: tributyl-amine; bis(tri-n-butylammonium) pyrophosphate / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere

2.2: 1 h / 20 °C / pH 7.5 / Inert atmosphere; aq. buffer

With tributyl-amine; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; bis(tri-n-butylammonium) pyrophosphate; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1002/anie.201106516

Reference yield:

: 7-[1-(5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-7-deaza-2’-deoxyguanosine

: 1372854-73-3
7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

: 1372854-72-2
7-[(R)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Guidance literature:: 7-[1-(5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-7-deaza-2’-deoxyguanosine; With trimethyl phosphite; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; trichlorophosphate; at 0 ℃; for 6h; Inert atmosphere;

With tributyl-amine; bis(tri-n-butylammonium) pyrophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h; Inert atmosphere;

In N,N-dimethyl-formamide; at 20 ℃; for 1h; pH=7.5; Inert atmosphere;

Reference yield:

: C₂₆H₃₆N₅O₁₁P

: 1372854-73-3
7-[(S)-1-(5-methoxy-2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-7-deaza-2'-deoxyguanosine-5'-triphosphate

Guidance literature:: C₂₆H₃₆N₅O₁₁P; With tributyl-amine; bis(tri-n-butylammonium) pyrophosphate; In N,N-dimethyl-formamide; for 0.166667h; Inert atmosphere;

In N,N-dimethyl-formamide; at 20 ℃; for 1h; pH=7.5; Inert atmosphere; aq. buffer;
DOI:10.1002/anie.201106516