2-Chloro-5-methoxypyridine

Base Information

Chemical Name:2-Chloro-5-methoxypyridine
CAS No.:139585-48-1
Molecular Formula:C6H6ClNO
Molecular Weight:143.573
Hs Code.:2933399090
European Community (EC) Number:846-748-9
DSSTox Substance ID:DTXSID90569474
Nikkaji Number:J1.782.615H
Wikidata:Q72453429
Mol file:139585-48-1.mol

Synonyms:2-CHLORO-5-METHOXYPYRIDINE;139585-48-1;Pyridine, 2-chloro-5-methoxy-;2-chloro-5-methoxy-pyridine;MFCD06659513;SCHEMBL942143;DTXSID90569474;ZXGHKJHRHVDMSW-UHFFFAOYSA-N;AKOS006239260;AB25956;AC-8282;CS-W005142;2-Chloro-5-methoxypyridine, AldrichCPR;AM803196;AS-14975;SY038294;EN300-53092;A807561

Suppliers and Price of 2-Chloro-5-methoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-methoxypyridine
100mg
$ 60.00

SynQuest Laboratories
2-Chloro-5-methoxypyridine
5 g
$ 228.00

SynQuest Laboratories
2-Chloro-5-methoxypyridine
1 g
$ 77.00

Matrix Scientific
2-Chloro-5-methoxypyridine 97%
10g
$ 900.00

Matrix Scientific
2-Chloro-5-methoxypyridine 97%
25g
$ 1800.00

Frontier Specialty Chemicals
2-Chloro-5-methoxypyridine 98%
1g
$ 45.00

Frontier Specialty Chemicals
2-Chloro-5-methoxypyridine 98%
5g
$ 120.00

Crysdot
2-Chloro-5-methoxypyridine 98%
25g
$ 396.00

Chemenu
2-Chloro-5-methoxypyridine 97%
10g
$ 203.00

Biosynth Carbosynth
2-Chloro-5-methoxypyridine
5 g
$ 535.90

Total 59 raw suppliers

Chemical Property of 2-Chloro-5-methoxypyridine

Chemical Property:

Appearance/Colour:Colorless to light yellow liquid
Vapor Pressure:0.236mmHg at 25°C
Refractive Index:1.517
Boiling Point:213.728 °C at 760 mmHg
PKA:-2.22±0.10(Predicted)
Flash Point:83.06 °C
PSA：22.12000
Density:1.21 g/cm³
LogP:1.74360
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:143.0137915
Heavy Atom Count:9
Complexity:89.1

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-5-methoxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CN=C(C=C1)Cl

Technology Process of 2-Chloro-5-methoxypyridine

There total 5 articles about 2-Chloro-5-methoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 41288-96-4
6-chloropyridine-3-ol

: 74-88-4
methyl iodide

: 139585-48-1
2-chloro-5-methoxypyridine

Guidance literature:: With sodium methylate; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 1.5h;

Reference yield: 50.0%

: 10167-97-2
2-amino-5-methoxypyridine

: 139585-48-1
2-chloro-5-methoxypyridine

Guidance literature:: 2-amino-5-methoxypyridine; With hydrogenchloride; sodium nitrite; at -5 ℃;

With hydrogenchloride; copper(l) chloride; at 0 - 70 ℃;
DOI:10.1002/ejoc.200300192

Reference yield:

: 5350-93-6
6-Chloro-pyridin-3-ylamine

: 139585-48-1
2-chloro-5-methoxypyridine

Guidance literature:: Multi-step reaction with 2 steps

1: NaNO₂, 1 N H₂SO₄, 2 N H₂SO₄

2: 32 percent / Na, methanol / dimethylsulfoxide

With methanol; sulfuric acid; sodium; sodium nitrite; In dimethyl sulfoxide;