2-Fluoro-4-nitrobenzonitrile

Base Information

Chemical Name:2-Fluoro-4-nitrobenzonitrile
CAS No.:34667-88-4
Molecular Formula:C7H3FN2O2
Molecular Weight:166.111
Hs Code.:29269090
European Community (EC) Number:672-522-2
DSSTox Substance ID:DTXSID10374628
Nikkaji Number:J545.374G
Wikidata:Q72475287
Mol file:34667-88-4.mol

Synonyms:2-fluoro-4-nitrobenzonitrile;34667-88-4;2-Fluoro-4-nitro-benzonitrile;Benzonitrile, 2-fluoro-4-nitro-;4-Nitro-2-fluorobenzonitrile;SCHEMBL361867;DTXSID10374628;UXBIHGQYRYAMFN-UHFFFAOYSA-N;AB3786;AC-996;MFCD04038715;AKOS006291848;AM61912;DS-1507;CS-0020166;FT-0647513;EN300-99982;A20970;J-019699

Suppliers and Price of 2-Fluoro-4-nitrobenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-4-nitrobenzonitrile
1g
$ 55.00

Matrix Scientific
2-Fluoro-4-nitrobenzonitrile 95+%
5g
$ 272.00

Matrix Scientific
2-Fluoro-4-nitrobenzonitrile 95+%
1g
$ 98.00

Frontier Specialty Chemicals
2-Fluoro-4-nitrobenzonitrile 98%
5g
$ 100.00

Frontier Specialty Chemicals
2-Fluoro-4-nitrobenzonitrile 98%
1g
$ 25.00

Frontier Specialty Chemicals
2-Fluoro-4-nitrobenzonitrile 98%
25g
$ 398.00

Crysdot
2-Fluoro-4-nitrobenzonitrile 98%
100g
$ 277.00

Chemenu
2-Fluoro-4-nitrobenzonitrile 95+%
100g
$ 262.00

Apolloscientific
2-Fluoro-4-nitrobenzonitrile
25g
$ 160.00

American Custom Chemicals Corporation
2-FLUORO-4-NITROBENZONITRILE 95.00%
5G
$ 1082.56

Total 47 raw suppliers

Chemical Property of 2-Fluoro-4-nitrobenzonitrile

Chemical Property:

Melting Point:70-71 °C
Boiling Point:306.517 °C at 760 mmHg
Flash Point:139.177 °C
PSA：69.61000
Density:1.419 g/cm³
LogP:2.12878
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:166.01785550
Heavy Atom Count:12
Complexity:229

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-4-nitrobenzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1[N+](=O)[O-])F)C#N

Technology Process of 2-Fluoro-4-nitrobenzonitrile

There total 9 articles about 2-Fluoro-4-nitrobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 350-32-3
2-fluoro-4-nitrobenzamide

: 34667-88-4
2-fluoro-4-nitrobenzonitrile

Guidance literature:: With Hexamethyldisiloxane; phosphorus pentoxide; In dichloromethane; at 100 ℃; for 4h;
DOI:10.1002/jhet.5570340412

Reference yield:

: 4110-33-2
2,4-dinitrobenzonitrile

: 3939-09-1,103496-86-2
2,4-difluorobenzonitrile

: 34667-88-4
2-fluoro-4-nitrobenzonitrile

Guidance literature:: With tetramethylammonium fluoride; In dimethyl sulfoxide; at 80 ℃; for 0.2h;
DOI:10.1039/c39930000921

Reference yield:

: 403-24-7
2-fluoro-4-nitrobenzoic acid

: 34667-88-4
2-fluoro-4-nitrobenzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: (COCl)2; DMF / tetrahydrofuran / 3 h / 0 - 20 °C

2: 15.5 g / NH₃ gas / tetrahydrofuran / 2.5 h / 0 °C

3: 14.7 g / Et₃N; (CF₃CO)2O / tetrahydrofuran / 16 h / 20 °C

With oxalyl dichloride; ammonia; triethylamine; N,N-dimethyl-formamide; trifluoroacetic anhydride; In tetrahydrofuran;
DOI:10.1021/jm010244+