2-amino>-1-phenylethanol

Base Information

• Chemical Name: 2-amino>-1-phenylethanol
• CAS No.: 73445-59-7
• Molecular Formula: C₁₇H₂₀ClNO₂
• Molecular Weight: 305.804
• Mol file: 73445-59-7.mol

Synonyms:2-amino>-1-phenylethanol

Chemical Property of 2-amino>-1-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino>-1-phenylethanol

There total 3 articles about 2-amino>-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

styrene oxide (96-09-3) + 3-chloro-4-methoxyphenethylamine (7569-87-1) → 2-amino>-1-phenylethanol (73445-59-7)

Guidance literature:

In tetrahydrofuran; for 18h; Heating;

DOI:10.1021/jm00021a018

Reference yield:

styrene oxide (96-09-3) + 3-chloro-4-methoxyphenethylamine (7569-87-1) + di-isopropyl ether (108-20-3) → 2-amino>-1-phenylethanol (73445-59-7)

Guidance literature:

In acetonitrile;

Reference yield:

2-(3-chloro-4-methoxyphenyl)acetonitrile (7569-58-6) → 2-amino>-1-phenylethanol (73445-59-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / LiAlH₄, 98percent H₂SO₄ / tetrahydrofuran / 1 h / Ambient temperature

2: 50 percent / tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran;

DOI:10.1021/jm00021a018

upstream raw materials:

styrene oxide

3-chloro-4-methoxyphenethylamine

2-(3-chloro-4-methoxyphenyl)acetonitrile

di-isopropyl ether

Downstream raw materials:

(+/-)-7-chloro-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

7-chloro-8-methoxy-3-butyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

(+/-)-7-chloro-8-methoxy-3-(4-aminobutyl)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

(+/-)-7-chloro-8-methoxy-3-(6-aminohexyl)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine