(S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate

Base Information

• Chemical Name: (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate
• CAS No.: 1380503-45-6
• Molecular Formula: C₁₅H₂₁NO₃
• Molecular Weight: 263.337
• Mol file: 1380503-45-6.mol

Synonyms:(S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate

Chemical Property of (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate

There total 17 articles about (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(S)-4-hydroxy-N,N-dimethyl-5-phenylpentanamide (924893-94-7) + acetic anhydride (108-24-7) → (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate (1380503-45-6)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 6h; optical yield given as %ee;

DOI:10.1002/ejoc.201101800

Reference yield: 50.0%

4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate (1380503-44-5) → (R)-4-hydroxy-N,N-dimethyl-5-phenylpentanamide (1380503-46-7) + (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate (1380503-45-6)

Guidance literature:

With Candida rugosa lipase; In acetone; at 37 ℃; for 96h; pH=7; optical yield given as %ee; enantioselective reaction; aq. phosphate buffer;

DOI:10.1002/ejoc.201101800

Reference yield: 30.0%

4-hydroxy-N,N-dimethyl-5-phenylpentanamide (924893-87-8) + Isopropenyl acetate (108-22-5) → (S)-4-hydroxy-N,N-dimethyl-5-phenylpentanamide (924893-94-7) + (R)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate + (S)-4-(dimethylcarbamoyl)-1-phenyl-2-butyl acetate (1380503-45-6)

Guidance literature:

With immobilized pseudomonas cepacia lipase; In tert-butyl methyl ether; at 20 ℃; for 93h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/ejoc.201101800

upstream raw materials:

4-hydroxy-N,N-dimethyl-5-phenylpentanamide

Isopropenyl acetate

(S)-4-hydroxy-N,N-dimethyl-5-phenylpentanamide

acetic anhydride