4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID

Base Information

• Chemical Name: 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
• CAS No.: 161622-14-6
• Molecular Formula: C8H4BrF3O2
• Molecular Weight: 269.018
• Hs Code.: 2916399090
• Mol file: 161622-14-6.mol

Synonyms:4-Bromo-3-(trifluoromethyl)benzoicacid;4-Bromo-α,α,α-trifluoro-m-toluic acid;

Chemical Property of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID

Chemical Property:

• Appearance/Colour: White crystalline powder
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.516
• Boiling Point: 289.2 °C at 760 mmHg
• PKA: 3.54±0.10(Predicted)
• Flash Point: 128.7 °C
• PSA: 37.30000
• Density: 1.773 g/cm³
• LogP: 3.16610
• Storage Temp.: Sealed in dry,Room Temperature
• Sensitive.: Light Sensitive/Air Sensitive

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-3-(trifluoromethyl)benzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID

There total 3 articles about 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-3-(trifluoromethyl)benzonitrile (1735-53-1) → 4-bromo-3-(trifluoromethyl)benzoic acid (161622-14-6)

Guidance literature:

With sulfuric acid; water; at 100 ℃;

Reference yield:

4-bromobenzenecarbonitrile (623-00-7) → 4-bromo-3-(trifluoromethyl)benzoic acid (161622-14-6)

Guidance literature:

Multi-step reaction with 2 steps

1: silver carbonate; sodium carbonate; dipotassium peroxodisulfate; sulfuric acid / dichloromethane / 10 h / 120 °C / Schlenk technique; Sealed tube

2: sodium hydroxide; water / ethanol / 6 h / Reflux

With dipotassium peroxodisulfate; sulfuric acid; water; sodium carbonate; silver carbonate; sodium hydroxide; In ethanol; dichloromethane;

DOI:10.1021/ol503189j

Reference yield:

→ 4-bromo-3-(trifluoromethyl)benzoic acid (161622-14-6)

Guidance literature:

With dmap; In tert-butyl alcohol; at 50 ℃;

upstream raw materials:

4-bromo-3-(trifluoromethyl)benzonitrile

4-bromobenzenecarbonitrile

Downstream raw materials:

4-bromo-3-trifluoromethylbenzoic acid methyl ester

(4-bromo-3-(trifluoromethyl)phenyl)methanol

4-bromo-3-trifluoromethyl-benzoic acid ethyl ester

4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-benzoic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 161622-14-6 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send