ethynyl(phenyl)iodonium triflate

Base Information

• Chemical Name: ethynyl(phenyl)iodonium triflate
• CAS No.: 1148038-45-2
• Molecular Formula: C₉H₆F₃IO₃S
• Molecular Weight: 378.111
• Mol file: 1148038-45-2.mol

Synonyms:ethynyl(phenyl)iodonium triflate

Chemical Property of ethynyl(phenyl)iodonium triflate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of ethynyl(phenyl)iodonium triflate

There total 3 articles about ethynyl(phenyl)iodonium triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

trifluoromethylsulfonic anhydride (358-23-6) + [bis(acetoxy)iodo]benzene (3240-34-4) + tributylethynyltin (994-89-8) → ethynyl(phenyl)iodonium triflate (1148038-45-2)

Guidance literature:

In dichloromethane; for 1.5h; Inert atmosphere;

DOI:10.1021/acs.joc.0c00781

Reference yield: 76.0%

(2-(trimethylsilyl)ethynyl)(phenyl)iodonium trifluoromethanesulfonate → ethynyl(phenyl)iodonium triflate (1148038-45-2)

Guidance literature:

With hydrogen fluoride; In dichloromethane; water; at 20 ℃; for 2h;

DOI:10.1021/jo2015467

Reference yield:

[bis(acetoxy)iodo]benzene (3240-34-4) → ethynyl(phenyl)iodonium triflate (1148038-45-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

2: hydrogen fluoride / dichloromethane; water / 2 h / 20 °C

With hydrogen fluoride; In dichloromethane; water; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

DOI:10.1021/jo2015467

upstream raw materials:

[bis(acetoxy)iodo]benzene

trifluoromethylsulfonic anhydride

tributylethynyltin

Downstream raw materials:

N-ethynyl-4-methyl-N-(2-((trimethylsilyl)ethynyl)phenyl)benzenesulfonamide

methyl 2-[ethynyl(toluene-4-sulfonyl)amino]pent-4-enoate

Refernces

• 1、 Kitamura, Tsugio,Morshed, Mohammad Hasan,Tsukada, Satoru,Miyazaki, Yuki,Iguchi, Naomi,Inoue, Daisuke. "Alkynylation of benzotriazole with silylethynyliodonium triflates. Regioselective synthesis of 2-ethynyl-2H-benzotriazole derivatives". . p. 8117 - 8120. Retrieved 2011.