4-BROMO-BENZOTHIAZOL-5-YLAMINE

Base Information

• Chemical Name: 4-BROMO-BENZOTHIAZOL-5-YLAMINE
• CAS No.: 769-19-7
• Molecular Formula: C₇H₅BrN₂S
• Molecular Weight: 229.1
• Hs Code.: 2934200090
• Mol file: 769-19-7.mol

Synonyms:Benzothiazole,5-amino-4-bromo- (7CI,8CI);4-Bromobenzothiazole-5-amine;5-Amino-4-bromobenzothiazole;

Chemical Property of 4-BROMO-BENZOTHIAZOL-5-YLAMINE

Chemical Property:

• Vapor Pressure: 2.4E-05mmHg at 25°C
• Melting Point: 115 °C
• Refractive Index: 1.783
• Boiling Point: 359.3 °C at 760 mmHg
• PKA: 0.50±0.10(Predicted)
• Flash Point: 171.1 °C
• PSA: 67.15000
• Density: 1.836 g/cm³
• LogP: 3.22220
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromobenzo[d]thiazol-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-BENZOTHIAZOL-5-YLAMINE

There total 3 articles about 4-BROMO-BENZOTHIAZOL-5-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-aminobenzothiazole (1123-93-9) → 4-bromobenzo[d]thiazol-5-amine (769-19-7)

Guidance literature:

With bromine; In chloroform;

DOI:10.1039/jr9650002248

Reference yield:

ammonium hydroxide (1336-21-6) + 5-aminobenzothiazole (1123-93-9) → (4-Bromobenzothiazol-5-yl)quanidine + 4-bromobenzo[d]thiazol-5-amine (769-19-7)

Guidance literature:

With bromine; In dichloromethane; chloroform; ethyl acetate;

Reference yield:

5-nitrobenzothiazole (2942-07-6) → 4-bromobenzo[d]thiazol-5-amine (769-19-7)

Guidance literature:

Multi-step reaction with 2 steps

1: tin(II) chloride dihdyrate / ethyl acetate / Reflux

2: bromine / chloroform / 1 h / 10 - 20 °C

With tin(II) chloride dihdyrate; bromine; In chloroform; ethyl acetate;

upstream raw materials:

5-aminobenzothiazole

ammonium hydroxide

5-nitrobenzothiazole

Downstream raw materials:

4,6-Dibrombenzothiazol

Refernces

• 1、 -. "CHEMICAL COMPOUNDS". Page/Page column 23-24. . Retrieved 2009/05/28.