1123-93-9

Basic information

• Product Name: 1,3-BENZOTHIAZOL-5-AMINE
• Synonyms: CHEMBRDG-BB 4003348;BENZOTHIAZOL-5-YLAMINE;BENZOTHIAZOL-5-YLAMINE HYDROCHLORIDE;1,3-BENZOTHIAZOL-5-AMINE;1,3-BENZOTHIAZOL-5-YLAMINE;5-BENZOTHIAZOLAMINE;5-BENZOTHIAZOLAMINE HYDROCHLORIDE;benzothiazol-5-amine
• CAS NO: 1123-93-9
• Molecular Formula: C7H6N2S
• Molecular Weight: 150.2
• EINECS: 214-381-8
• Product Categories: BENZOTHIAZOLE
• Mol File: 1123-93-9.mol
• Article Data: 17

Chemical Properties

• Melting Point: 55 °C
• Boiling Point: 323.07 °C at 760 mmHg
• Flash Point: 149.188 °C
• Appearance: /
• Density: 1.383
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.44±0.10(Predicted)
• Water Solubility: Sparingly soluble in water.(0.26 g/L) (25°C),
• CAS DataBase Reference: 1,3-BENZOTHIAZOL-5-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-BENZOTHIAZOL-5-AMINE(1123-93-9)
• EPA Substance Registry System: 1,3-BENZOTHIAZOL-5-AMINE(1123-93-9)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-36-22
• Safety Statements: 22-26-36/37/39
• RIDADR: 2811
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 1123-93-9(Hazardous Substances Data)

Usage

Uses

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

InChI:InChI=1/C7H6N2S/c8-5-1-2-7-6(3-5)9-4-10-7/h1-4H,8H2

Upstream product

• 2942-07-6 5-nitrobenzothiazole 
• 21715-13-9 2,4-diaminobenzenethiol 
• 122-51-0 orthoformic acid triethyl ester 
• 10403-47-1 2-bromo 5-nitroaniline 
• 58759-63-0 5-nitrobenzo[d]thiazole-2(3H)-thione 
• 53666-48-1 N-(2-chloro-5-nitrophenyl)formamide 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 98556-09-3 N-(2-bromo-5-nitrophenyl)formamide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 36894-61-8 N-(benzo[d]thiazol-5-yl)acetamide 
• 50480-29-0 benzo[d]thiazole-2,5-diamine 
• 58249-68-6 5-acetoxy-benzothiazole 
• 18463-90-6 5-p-dimethylaminophenylazobenzthiazole 
• 768-11-6 5-bromo-benzthiazole 
• 769-19-7 4-bromobenzo[d]thiazol-5-amine 
• 58249-57-3 1,3-benzothiazole-5-carbonitrile 
• 149474-18-0 5-(2'-Carboxyphenylamino)benzothiazole 
• 744261-37-8 N-benzothiazol-5-yl-6-(4-fluorophenyl)-2-methylnicotinamide 
• 1253575-34-6 N-(3-(4-(bis(4-methoxybenzyl)amino)-6-methyl-1,3,5-triazin-2-yl)-5-((4-(methylsulfonyl)piperazin-1-yl)methyl)pyridin-2-yl)benzo[d]thiazol-5-amine 
• 256415-35-7 C₁₄H₁₁N₃S₂ 
• 1360449-09-7 1,3-di(benzo[d]thiazol-5-yl)thiourea 
• 1610793-27-5 diphenyl (benzo[d]thiazol-5-ylamino)(2-cyclopropylpyrimidin-4-yl)methylphosphonate 

Relevant articles and documents

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ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I" PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

Visible-Light-Photocatalyzed Reductions of N-Heterocyclic Nitroaryls to Anilines Utilizing Ascorbic Acid Reductant

A photoreductive protocol utilizing [Ru(bpy)3]2+ photocatalyst, blue light LEDs, and ascorbic acid (AscH2) has been developed to reduce nitro N-heteroaryls to the corresponding anilines. Based on experimental and computational results and previous studies, we propose that the reaction proceeds via proton-coupled electron transfer between AscH2, photocatalyst, and the nitro N-heteroaryl. The method offers a green catalytic procedure to reduce, e.g., 4-/8-nitroquinolines to the corresponding aminoquinolines, substructures present in important antimalarial drugs.