C₃₅H₃₇N₅O₉

Base Information

• Chemical Name: C₃₅H₃₇N₅O₉
• CAS No.: 1363735-96-9
• Molecular Formula: C₃₅H₃₇N₅O₉
• Molecular Weight: 671.707
• Mol file: 1363735-96-9.mol

Synonyms:C₃₅H₃₇N₅O₉

Chemical Property of C₃₅H₃₇N₅O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₃₅H₃₇N₅O₉

There total 1 articles about C₃₅H₃₇N₅O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C33H35N5O8 (1263796-39-9) + acetic anhydride (108-24-7) → C35H37N5O9 (1363735-96-9)

Guidance literature:

With pyridine; at 20 ℃; for 14h; Inert atmosphere;

DOI:10.1002/chem.201102287

Reference yield: 67.0%

C35H37N5O9 (1363735-96-9) → 2'-O-(2-azidoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine (1363735-99-2)

Guidance literature:

C₃₅H₃₇N₅O₉; With pyridine; 1,2,4-Triazole; for 0.25h; Inert atmosphere;

With trichlorophosphate; at 0 - 20 ℃; for 36h; Inert atmosphere;

With ammonia; In water; at 20 ℃; for 19h; Inert atmosphere;

DOI:10.1002/chem.201102287

Reference yield:

C35H37N5O9 (1363735-96-9) → 2'-O-(2-aminoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine (1363736-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine; 1,2,4-Triazole / 0.25 h / Inert atmosphere

1.2: 36 h / 0 - 20 °C / Inert atmosphere

1.3: 19 h / 20 °C / Inert atmosphere

2.1: water; triphenylphosphine / tetrahydrofuran / 12 h / 45 °C / Inert atmosphere

With pyridine; 1,2,4-Triazole; water; triphenylphosphine; In tetrahydrofuran;

DOI:10.1002/chem.201102287

upstream raw materials:

C₃₃H₃₅N₅O₈

acetic anhydride

Downstream raw materials:

2'-O-(2-azidoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine

2'-O-(2-aminoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine

2'-O-(N-Fmoc)aminoethyl-5'-O-(4,4'-dimethoxytrityl)-4-N-Fmoc-5-methylcytidine