1263796-39-9

Upstream product

• 1263796-38-8 C₃₄H₃₈N₂O₁₁S 
• 212061-57-9 2'-O-(2-Hydroxyethyl)-5'-O-dimethoxytrityl-5-methyluridine 
• 817623-11-3 2,2'-anhydro-1-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl-5-methyluridine] 
• 22423-26-3 O-2,2'-cyclo-5-methyluridine 
• 1463-10-1 5-Methyluridine 

Downstream Products

• 1363735-99-2 2'-O-(2-azidoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine 
• 1363736-01-9 2'-O-(2-aminoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine 
• 1363736-03-1 2'-O-(N-Fmoc)aminoethyl-5'-O-(4,4'-dimethoxytrityl)-4-N-Fmoc-5-methylcytidine 
• 1363735-96-9 C₃₅H₃₇N₅O₉ 
• 1412707-66-4 2'-O-{2-[3-(7,8-didehydro-1,2:5,6-dibenzocyclooctynyl)oxyamido]ethyl}-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine 3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 
• 242147-79-1 2'-O-[2-(amino)ethyl]-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine 

Relevant academic research and scientific papers

OLIGONUCLEOTIDE LIGATION

A method for joining oligonucleotides. The method includes joining together one or more oligonucleotides by reacting an alkyne group lined to an oligonucleotide with an azide group linked to an oligonucleotide to form a triazole linkage. The alkyne group is a strained alkyne group. The method can include ligating together ends of one or more oligonucleotides or cross-linking strands of an oligonucleotide duplex. The methods described allow oligonucleotide strands to be ligated together without the need for a ligase enzyme.