(E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane

Base Information

• Chemical Name: (E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane
• CAS No.: 1338228-99-1
• Molecular Formula: C₂₂H₂₁FOSi
• Molecular Weight: 348.492
• Mol file: 1338228-99-1.mol

Synonyms:(E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane

Chemical Property of (E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane

There total 1 articles about (E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

para-iodoanisole (696-62-8) + (α-Fluorovinyl)diphenylmethylsilane (257610-49-4) → (E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane (1338228-99-1)

Guidance literature:

With palladium diacetate; silver carbonate; In 1,4-dioxane; at 90 ℃; for 5h; optical yield given as %de; stereoselective reaction; Molecular sieve;

DOI:10.1021/jo201720x

Reference yield: 99.0%

(E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane (1338228-99-1) → (Z)-1-Fluoro-2-(4-methoxyphenyl)ethylene (26928-26-7)

Guidance literature:

(E)-[1-fluoro-2-(4-methoxyphenyl)vinyl]methyldiphenylsilane; With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 1h;

With water; In dimethyl sulfoxide; stereoselective reaction;

DOI:10.1021/jo201720x

upstream raw materials:

para-iodoanisole

(α-Fluorovinyl)diphenylmethylsilane

Downstream raw materials:

(Z)-1-Fluoro-2-(4-methoxyphenyl)ethylene