257610-49-4 Usage
Description
(1-Fluorovinyl)methyldiphenylsilane is an organosilicon compound characterized by its fluorovinyl group and diphenylmethylsilane structure. It is a versatile reagent in organic synthesis, particularly in the preparation of fluorinated organic compounds.
Uses
Used in Pharmaceutical Industry:
(1-Fluorovinyl)methyldiphenylsilane is used as a reagent for the preparation of fluoro C-glycosyl asparagine from C-formyl glucoside. This process involves fluorovinylation and Claisen rearrangement, which are crucial for the construction of the α-amino acid moiety. The α-amino acid moiety is an essential component in the synthesis of various pharmaceutical compounds, making (1-Fluorovinyl)methyldiphenylsilane a valuable tool in the development of new drugs and therapeutic agents.
Additionally, the compound may have potential applications in other industries, such as materials science, where fluorinated compounds are often sought for their unique properties. However, the provided materials do not specify any other industries or applications for (1-Fluorovinyl)methyldiphenylsilane.
Check Digit Verification of cas no
The CAS Registry Mumber 257610-49-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,7,6,1 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 257610-49:
(8*2)+(7*5)+(6*7)+(5*6)+(4*1)+(3*0)+(2*4)+(1*9)=144
144 % 10 = 4
So 257610-49-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H15FSi/c1-13(16)17(2,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-12H,1H2,2H3
257610-49-4Relevant articles and documents
Fluoride ion-initiated α-fluorovinylation of carbonyl compounds with α-fluorovinyldiphenylmethylsilane
Hanamoto, Takeshi,Harada, Shigeo,Shindo, Keiko,Kondo, Michio
, p. 2397 - 2398 (1999)
α-Fluorovinyldiphenylmethylsilane was synthesized in one step from 1,1- difluoroethylene; the TBAF-initiated reaction of the silane with carbonyl compounds smoothly proceeded to give the corresponding α-fluoroallylic alcohols in good yields.
