5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine

Base Information

• Chemical Name: 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine
• CAS No.: 79379-55-8
• Molecular Formula: C₂₁H₂₄N₂O₂
• Molecular Weight: 336.434
• Mol file: 79379-55-8.mol

Synonyms:5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine

Chemical Property of 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine

There total 2 articles about 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-(1-phenyl-propenyl)-morpholine (30085-70-2,39655-41-9,66217-92-3) + 2-bromo-1-phenyl-ethanone oxime (14181-72-7,17082-13-2,17082-14-3) → 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine (79379-55-8)

Guidance literature:

In toluene; for 3h; Ambient temperature;

DOI:10.1246/bcsj.63.3595

Reference yield: 78.0%

2-bromo-1-phenyl-ethanone oxime (14181-72-7,17082-13-2,17082-14-3) + [E]-1-morpholino-1-phenyl-1-propene (30085-70-2) → 5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine (79379-55-8)

Guidance literature:

In toluene; for 3h; Ambient temperature;

DOI:10.1246/cl.1981.869

Reference yield: 58.0%

5-Methyl-6-morpholin-4-yl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine (79379-55-8) → 3‐methyl‐2,5‐diphenyl‐1H‐pyrrole (16206-34-1)

Guidance literature:

With triiron dodecarbonyl; In 1,2-dichloro-ethane; at 80 ℃; for 3h;

DOI:10.1246/bcsj.63.3595 DOI:10.1246/cl.1981.869

upstream raw materials:

4-(1-phenyl-propenyl)-morpholine

2-bromo-1-phenyl-ethanone oxime

[E]-1-morpholino-1-phenyl-1-propene

Downstream raw materials:

3‐methyl‐2,5‐diphenyl‐1H‐pyrrole

5-Methyl-3,6-diphenyl-5,6-dihydro-4H-[1,2]oxazine