4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester

Base Information

Chemical Name:4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester
CAS No.:1228564-89-3
Molecular Formula:C₂₅H₂₄ClN₇O₂
Molecular Weight:489.964
Hs Code.:

Synonyms:4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester

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Chemical Property of 4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester

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Technology Process of 4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester

There total 1 articles about 4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 100-55-0
3-hydroxymethylpyridin

: 1228565-08-9
(2-chloro-benzyl)-(5-piperazin-1-yl-pyrido[4,3-d]pyrimidin-2-yl)-amine hydrochloride

: 530-62-1
1,1'-carbonyldiimidazole

: 1228564-89-3
4-[2-(2-chloro-benzylamino)-pyrido[4,3-d]pyrimidin-5-yl]-piperazine-1-carboxylic acid pyridin-3-ylmethyl ester

Guidance literature:: 3-hydroxymethylpyridin; 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 3h;

(2-chloro-benzyl)-(5-piperazin-1-yl-pyrido[4,3-d]pyrimidin-2-yl)-amine hydrochloride; In tetrahydrofuran; at 20 ℃; for 18h;