2-Chloropropane

Base Information

• Chemical Name: 2-Chloropropane
• CAS No.: 75-29-6
• Molecular Formula: C3H7Cl
• Molecular Weight: 78.5416
• Hs Code.: 2903199000
• European Community (EC) Number: 200-858-8
• UN Number: 2356
• UNII: VU39J8AJ2N
• DSSTox Substance ID: DTXSID6047739
• Nikkaji Number: J1.449D
• Wikipedia: Isopropyl_chloride
• Wikidata: Q209360
• Mol file: 75-29-6.mol

Synonyms:2-CHLOROPROPANE;75-29-6;Isopropyl chloride;Propane, 2-chloro-;Isopropylchloride;2-Propyl chloride;sec-Propyl chloride;Chlorodimethylmethane;Narcosop;Isoprid;2-CHLORO-PROPANE;CCRIS 874;HSDB 5204;EINECS 200-858-8;UN2356;UNII-VU39J8AJ2N;BRN 1730782;VU39J8AJ2N;AI3-18025;EC 200-858-8;4-01-00-00191 (Beilstein Handbook Reference);MFCD00000867;2-CHLOROPROPANE (1,1,1,2,3,3,3-D7);2-chloro-propan;iso-propyl chloride;Propano, 2-cloro-;iso-C3H7Cl;C3H7Cl;2-Chloropropane, 99%;CHLOROPROPANE, 2-;2-Chloropropane, >=99%;2-CHLOROPROPANE [HSDB];ISOPROPYL CHLORIDE [MI];DTXSID6047739;2-Chloropropane, analytical standard;NA2356;STL480907;AKOS009156966;(2-Chloropropane);UN 2356;Isopropyl chloride [Propane, 2-chloro-];LS-119656;FT-0612007;2-Chloropropane [UN2356] [Flammable liquid];EN300-139045;2-Chloropropane [UN2356] [Flammable liquid];Q209360;J-504537;Q-200264;F0001-1898

Chemical Property of 2-Chloropropane

Chemical Property:

• Appearance/Colour: colorless liquid with pleasant smells
• Melting Point: -118 °C
• Refractive Index: n20/D 1.395(lit.)
• Boiling Point: 37.254 °C at 760 mmHg
• Flash Point: -35 °C
• PSA: 0.00000
• Density: 0.874 g/cm³
• LogP: 1.63360
• Water Solubility.: 3.1 g/L (20℃)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 78.0236279
• Heavy Atom Count: 4
• Complexity: 10.8
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F+, Xi, Xn, F
• Hazard Codes: F:Flammable;;
• Statements: R11:; R20/21/22:
• Safety Statements: S29:; S9:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorinated Aliphatics
• Canonical SMILES: CC(C)Cl

Technology Process of 2-Chloropropane

There total 132 articles about 2-Chloropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

isopropyl o-(N-methylcarbamoyl)phenyl sulphoxide → 2-methyl-1,2-benzisothiazole-3(2H)-one (2527-66-4) + isopropyl chloride (75-29-6)

Guidance literature:

With thionyl chloride; In tetrachloromethane; for 2h; Heating;

Reference yield: 94.0%

isopropyl alcohol (67-63-0,8013-70-5) → diisopropyl hydrogenphosphonate (1809-20-7) + isopropyl chloride (75-29-6)

Guidance literature:

With phosphorus trichloride; at 0 - 50 ℃; for 50h;

DOI:10.1080/10426500903444366

Reference yield: 84.0%

1,4-diisopropylcyclohexa-2,5-diene-1,4-dicarboxylic acid → isopropyl chloride (75-29-6) + p-isopropylbenzoic acid (536-66-3)

Guidance literature:

With chlorosulfonic acid; In dichloromethane; at 0 ℃;

DOI:10.1002/adsc.201000322

upstream raw materials:

propan-1-ol

2-iodo-propane

tetrachloromethane

propane

Downstream raw materials:

4-isobutylpyridine

methyl 3-(isopropyl)benzoate

methyl 5-isopropylfuran-2-carboxylate

isopropyl-pentachlorophenyl ether

Refernces

• 1、 Aboulaich,Boury,Mutin. "Reactive and organosoluble anatase nanoparticles by a surfactant-free nonhydrolytic synthesis". . p. 4519 - 4521. Retrieved 2010.
• 2、 Crowell,Jones. "". . p. 3506. Retrieved 1951.
• 3、 Nash,Taylor,Doering. "-". . p. 1516. Retrieved 1949.
• 4、 -. "METHODS AND SYSTEMS TO FORM PROPYLENE CHLOROHYDRIN AND PROPYLENE OXIDE". Paragraph 164. . Retrieved 2019/01/05.
• 5、 Escamilla-Pérez, Angel Manuel,Louvain, Nicolas,Boury, Bruno,Brun, Nicolas,Mutin, P. Hubert. "Ethers as Oxygen Donor and Carbon Source in Non-hydrolytic Sol–Gel: One-Pot, Atom-Economic Synthesis of Mesoporous TiO2–Carbon Nanocomposites". supporting information. p. 4982 - 4990. Retrieved 2018/03/06.