C₁₀H₁₁O₂I

Base Information

• Chemical Name: C₁₀H₁₁O₂I
• CAS No.: 880134-35-0
• Molecular Formula: C₁₀H₁₁IO₂
• Molecular Weight: 290.101
• Mol file: 880134-35-0.mol

Synonyms:C₁₀H₁₁O₂I

Chemical Property of C₁₀H₁₁O₂I

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₁₁O₂I

There total 6 articles about C₁₀H₁₁O₂I which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + (2-iodo-5-methyl-phenyl)-acetic acid (220991-52-6) → C10H11O2I (880134-35-0)

Guidance literature:

With sulfuric acid; for 3h; Reflux;

DOI:10.1002/anie.201603576

Reference yield:

m-methylphenylacetic acid (621-36-3) → C10H11O2I (880134-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium diacetate; iodine; [bis(acetoxy)iodo]benzene / N,N-dimethyl-formamide / 12 h / 60 °C / Darkness

2: sulfuric acid / 3 h / Reflux

With [bis(acetoxy)iodo]benzene; sulfuric acid; iodine; palladium diacetate; In N,N-dimethyl-formamide;

DOI:10.1002/anie.201603576

Reference yield:

2-iodoyl-5-methylbenzoic acid (52548-14-8) → C10H11O2I (880134-35-0)

Guidance literature:

Multi-step reaction with 3 steps

1: (COCl)2

2: silver oxide / Heating

With oxalyl dichloride; silver(l) oxide; 3: Arndt-Eistert rearrangement;

DOI:10.1002/jlcr.1273

upstream raw materials:

methanol

C₉H₇OIN₂

2-iodoyl-5-methylbenzoic acid

2-iodo-5-methylbenzoyl chloride