(E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

Base Information

Chemical Name:(E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester
CAS No.:400610-89-1
Molecular Formula:C₁₉H₂₁F₃N₄O₂
Molecular Weight:394.397
Hs Code.:

Synonyms:(E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

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Technology Process of (E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

There total 2 articles about (E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 400610-88-0
(E)-4-cyclopentyl-2-iodo-but-2-enoic acid methyl ester

: 400610-45-9
1-(4-bromo-2-trifluoromethyl-phenyl)-5-methyl-1H-tetrazole

: 106-93-4
ethylene dibromide

: 400610-89-1
(E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

Guidance literature:: With chloro-trimethyl-silane; triphenylphosphine; zinc; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; ethyl acetate;

Reference yield: 65.0%

: 400610-88-0
(E)-4-cyclopentyl-2-iodo-but-2-enoic acid methyl ester

: 400610-45-9
1-(4-bromo-2-trifluoromethyl-phenyl)-5-methyl-1H-tetrazole

: 400610-89-1
(E)-4-cyclopentyl-2-[4-(5-methyl-tetrazol-1-yl)-3-trifluoromethyl-phenyl]-but-2-enoic acid methyl ester

Guidance literature:: With chloro-trimethyl-silane; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; zinc; In tetrahydrofuran; at 25 - 45 ℃; for 23.42h;