2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

Base Information

Chemical Name:2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide
CAS No.:472981-27-4
Molecular Formula:BrH*C₁₈H₁₇N₅OS
Molecular Weight:432.344
Hs Code.:

Synonyms:2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

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Chemical Property of 2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

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Technology Process of 2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

There total 4 articles about 2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.5%

: 1116559-13-7
2-bromo-1-(2-methylimidazo[1,2-a]pyrimidin-3-yl)ethanone monohydrobromide

: 880-29-5
1-(4-ethoxyphenyl)thiourea

: 472981-27-4
2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

Guidance literature:: In ethanol; at 20 ℃; Heating / reflux;

Reference yield:

: 100289-21-2
1-(2-Methylimidazo<1,2-a>pyrimidin-3-yl)ethanon

: 472981-27-4
2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / acetic acid / 20 - 110 °C

2: ethanol / 21 h / 20 °C / Reflux

With bromine; In ethanol; acetic acid;

Reference yield:

: 1694-29-7
3-chloropentane-2,4-dione

: 472981-27-4
2-(4-ethoxyphenylamino)-4-(2-methyl-imidazo[1,2-a]pyrimidin-3-yl)thiazole monohydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 40 h / Reflux

2: bromine / acetic acid / 20 - 110 °C

3: ethanol / 21 h / 20 °C / Reflux

With bromine; In ethanol; acetic acid;