7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline

Base Information

• Chemical Name: 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline
• CAS No.: 1261073-29-3
• Molecular Formula: C₁₈H₁₈N₂O₃
• Molecular Weight: 310.353
• Mol file: 1261073-29-3.mol

Synonyms:7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline

Chemical Property of 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline

There total 2 articles about 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone (7702-09-2) + 4-methyl-1,2-diaminobenzene (496-72-0) → 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline (1261073-29-3) + C18H18N2O3 (1261073-28-2)

Guidance literature:

2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone; 4-methyl-1,2-diaminobenzene; With copper(II) bis(trifluoromethanesulfonate); In diethyl ether; 1,2-dichloro-ethane; at 110 ℃; under 5171.62 Torr;

In diethyl ether; 1,2-dichloro-ethane; at 110 ℃; under 5171.62 Torr;

DOI:10.1021/ol1027927

Reference yield:

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) → 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline (1261073-29-3) + C18H18N2O3 (1261073-28-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diethyl ether; 1,2-dichloro-ethane / 20 °C

1.2: polymer-supported fluoride / 0.7 h

2.1: copper(II) bis(trifluoromethanesulfonate) / diethyl ether; 1,2-dichloro-ethane / 110 °C / 5171.62 Torr

2.2: PL-SO₂Cl resin; PL-NCO resin; polymer-supported tosylhydrazine / 110 °C / 5171.62 Torr

With copper(II) bis(trifluoromethanesulfonate); In diethyl ether; 1,2-dichloro-ethane;

DOI:10.1021/ol1027927

upstream raw materials:

2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone

4-methyl-1,2-diaminobenzene

3,4,5-Trimethoxybenzoyl chloride

Refernces